Journal article
Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking
PloS one, Vol.12(3), pp.e0174354-e0174354
2017
DOI: 10.1371/journal.pone.0174354
PMCID: PMC5375129
PMID: 28362870
Abstract
Due to their relatively homogeneous lifestyle and living environment, the Amish offer a novel opportunity to study the health associations of tobacco smoke exposure, particularly secondhand smoke. We hypothesized that secondhand smoke exposure is associated with worse pulmonary and cardiometabolic health. We examined cross-sectional data on 3568 Amish study participants, including tobacco use and secondhand smoke exposure from family members included in the study. Thirty-four percent of Amish men reported ever smoking. Of this proportion, 64% used cigars, 46% cigarettes, and 21% pipes. Less than 1% of women reported ever smoking. Smoking was associated with lower spirometric lung function, higher body mass index, lower HDL cholesterol, higher heart rate, lower ankle-brachial index, and larger aortic diameter in men. A greater number of sources of secondhand smoke exposure (defined from the total of spouses, parents, and siblings who smoke) was associated with higher body mass index (p = 0.03) and with higher fasting glucose in men (p = 0.01), but not in women (p = 0.007 for sex*secondhand smoke interaction). Secondhand smoke exposure was also associated with reduced HDL cholesterol only in women (p = 0.002) and a lower heart rate only in men (p = 0.006). Smoking habits among the Old Order Amish are notable for the absence of female participation and a high proportion of cigar and pipe use. Smoking is associated with decreased spirometric indices of lung function and increased cardiovascular risk in this population and secondhand smoke exposure is associated with a greater burden of risk factors for cardiovascular disease. Sex differences in correlations could reflect differences in exposure patterns, mechanisms, or susceptibilities.
Details
- Title: Subtitle
- Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking
- Creators
- Robert M Reed - University of Maryland School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, United States of AmericaMark T Dransfield - University of Alabama School of Medicine, Division of Pulmonary and Critical Care Medicine, Birmingham, Alabama, United States of AmericaMichael Eberlein - University of Iowa School of Medicine, Division of Pulmonary and Critical Care Medicine, Iowa City, Iowa, United States of AmericaMichael Miller - University of Maryland School of Medicine, Department of Epidemiology and Public Health, Baltimore, Maryland, United States of AmericaGiora Netzer - University of Maryland School of Medicine, Department of Epidemiology and Public Health, Baltimore, Maryland, United States of AmericaMary Pavlovich - University of Maryland School of Medicine, Department of Epidemiology and Public Health, Baltimore, Maryland, United States of AmericaToni I Pollin - University of Maryland School of Medicine, Department of Epidemiology and Public Health, Baltimore, Maryland, United States of AmericaSteven M Scharf - University of Maryland School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, United States of AmericaAlan R Shuldiner - University of Maryland School of Medicine, Department of Epidemiology and Public Health, Baltimore, Maryland, United States of AmericaDon Sin - University of British Columbia Respiratory Medicine; Vancouver, British Columbia, CanadaBraxton D Mitchell - University of Maryland School of Medicine, Department of Epidemiology and Public Health, Baltimore, Maryland, United States of America
- Resource Type
- Journal article
- Publication Details
- PloS one, Vol.12(3), pp.e0174354-e0174354
- DOI
- 10.1371/journal.pone.0174354
- PMID
- 28362870
- PMCID
- PMC5375129
- NLM abbreviation
- PLoS One
- ISSN
- 1932-6203
- eISSN
- 1932-6203
- Publisher
- Public Library of Science
- Grant note
- DOI: 10.13039/100005640, name: Flight Attendant Medical Research Institute, award: 1400089; DOI: 10.13039/100000002, name: National Institutes of Health, award: 2 UL1 TR000442-06; DOI: 10.13039/100000738, name: U.S. Department of Veterans Affairs; DOI: 10.13039/100000002, name: National Institutes of Health, award: R01 HL088119-03; DOI: 10.13039/100000002, name: National Institutes of Health, award: U01 GM074518-05; DOI: 10.13039/100000002, name: National Institutes of Health, award: R01 HL69313; DOI: 10.13039/100000002, name: National Institutes of Health, award: 2 UL1 TR000442-06
- Language
- English
- Date published
- 2017
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
- Record Identifier
- 9984094573802771
Metrics
14 Record Views