Journal article
Gender-related differences in aneurysmal subarachnoid hemorrhage
Journal of neurosurgery, Vol.84(1), pp.43-48
01/1996
DOI: 10.3171/jns.1996.84.1.0043
PMID: 8613834
Abstract
Female gender is a recognized risk factor for the occurrence of aneurysmal subarachnoid hemorrhage. In the present study the authors analyzed differences in admission characteristics and outcome between 578 women (64%) and 328 men (36%) who were enrolled in a recently completed clinical trial. The female-to-male ratio was nearly 2:1. The women in the study were older than the men (mean age 51.4 years vs 47.3 years, respectively, p<0.001). Female patients harbored aneurysms of the internal carotid artery more frequently than male patients (36.8% vs. 18.0%, p<0.001) and more often had multiple aneurysms (32.4% vs. 17.6%, p<0.001). On the other hand, anterior cerebral artery aneurysms were more commonly encountered in men (46.1% in men vs. 26.6% in women, p<0.001). Other baseline prognostic factors were balanced between the gender groups. Surgery was performed equally in both sexes (98%), although the time to operation was shorter for women (mean 3.6 days for women vs. 5.3 days for men, p = 0.0002). In the placebo group, the occurrence of vasospasm was not statistically different between the two groups. Primary causes of death and disability were the same, and favorable outcome rates at 3 months were not statistically different between the genders (69.7% for women vs. 73.4% for men, p = 0.243). The odds of a favorable outcome in women versus one in men were not statistically significant either before of after adjustment for age. These observations lead the authors to suggest that although women are older and harbor more aneurysms, the 3-month outcome for women and men who experience aneurysmal subarachnoid hemorrhage is the same.
Details
- Title: Subtitle
- Gender-related differences in aneurysmal subarachnoid hemorrhage
- Creators
- Gail L Kongable - Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, USAGiuseppe LanzinoTeresa P GermansonLaura L TruskowskiWayne M AlvesJames C TornerNeal F Kassell
- Resource Type
- Journal article
- Publication Details
- Journal of neurosurgery, Vol.84(1), pp.43-48
- DOI
- 10.3171/jns.1996.84.1.0043
- PMID
- 8613834
- NLM abbreviation
- J Neurosurg
- ISSN
- 0022-3085
- eISSN
- 1933-0693
- Publisher
- United States
- Grant note
- NS24806 / NINDS NIH HHS
- Language
- English
- Date published
- 01/1996
- Academic Unit
- Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
- Record Identifier
- 9983996088302771
Metrics
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