Journal article
Gender-specific outcomes after balloon aortic valvuloplasty: Inhospital and long-term outcomes
The American heart journal, Vol.170(1), pp.180-186
07/2015
DOI: 10.1016/j.ahj.2015.03.013
PMID: 26093880
Abstract
Increasing numbers of balloon aortic valvuloplasty (BAV) are performed in the management of symptomatic aortic stenosis as bridge and therapeutic challenge in the work-up for transcatheter aortic valve replacement. However, the significance of gender in outcomes following BAV remains controversial.
We retrospectively reviewed 664 consecutive patients who underwent BAV from January 2005 to December 2012. Patients were stratified according to gender. Clinical and procedural characteristics as well as in-hospital outcomes and 1-year mortality were collected. Cumulative survival curves for women and men were constructed using the Kaplan-Meier method and were compared by the log-rank test. Cox regression analysis was performed to identify the independent effect of sex on 1-year mortality.
Of the 664 patients, 333 (52%) were women. Women had lower body surface area, tended to be frailer and were less likely to have history of coronary artery disease. Women were more likely to present with heart failure whereas men presented more commonly with chest pain. In hospital death was significantly higher in women compared to men, mainly driven by the difference in cardiac death (8.1% vs 3.9%, P = .02 and 6.3% vs 2.6%, P = .02 respectively). One-year mortality rates were similar in women and men (25.4% vs 29.4%, P = .42) and after multivariate analysis gender had no association with 1-year mortality (HR = 0.9, P = .65).
Significant differences exist in baseline characteristics and presentation between genders. Although in hospital mortality after BAV was significantly higher in women, 1-year mortality was similar between women and men.
Details
- Title: Subtitle
- Gender-specific outcomes after balloon aortic valvuloplasty: Inhospital and long-term outcomes
- Creators
- Georgios Christodoulidis - The Icahn School of Medicine at Mount Sinai, New York, NYJennifer Yu - The Icahn School of Medicine at Mount Sinai, New York, NYAnnapoorna Kini - The Icahn School of Medicine at Mount Sinai, New York, NYGeorge D Dangas - The Icahn School of Medicine at Mount Sinai, New York, NYUsman Baber - The Icahn School of Medicine at Mount Sinai, New York, NYAquino Melissa - The Icahn School of Medicine at Mount Sinai, New York, NYSamantha Sartori - The Icahn School of Medicine at Mount Sinai, New York, NYKleanthis Theodoropoulos - The Icahn School of Medicine at Mount Sinai, New York, NYArjun Bhat - The Icahn School of Medicine at Mount Sinai, New York, NYJason Kovacic - The Icahn School of Medicine at Mount Sinai, New York, NYPedro Moreno - The Icahn School of Medicine at Mount Sinai, New York, NYPrakash Krishnan - The Icahn School of Medicine at Mount Sinai, New York, NYRoxana Mehran - The Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: roxana.mehran@mountsinai.orgSamin Sharma - The Icahn School of Medicine at Mount Sinai, New York, NY
- Resource Type
- Journal article
- Publication Details
- The American heart journal, Vol.170(1), pp.180-186
- DOI
- 10.1016/j.ahj.2015.03.013
- PMID
- 26093880
- ISSN
- 0002-8703
- eISSN
- 1097-6744
- Language
- English
- Date published
- 07/2015
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094541002771
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