Gene therapy for vasospasm after subarachnoid hemorrhage

Kazunori Toyoda; Hiroaki Ooboshi; Hiroshi Nakane; Setsuro Ibayashi; Masatoshi Fujishima; Toshihiro Ueda; Donald D. Heistad

doi:10.3995/jstroke.22.468

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Gene therapy for vasospasm after subarachnoid hemorrhage

Journal article

Open access

Gene therapy for vasospasm after subarachnoid hemorrhage

Kazunori Toyoda, Hiroaki Ooboshi, Hiroshi Nakane, Setsuro Ibayashi, Masatoshi Fujishima, Toshihiro Ueda and Donald D. Heistad

Nōsotchū, Vol.22(3), pp.468-471

2000

DOI: 10.3995/jstroke.22.468

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Abstract

Gene transfer to cerebral arteries is an appealing strategy to modulate vascular function, and an possible technique for treatment of verebrovascular diseases. We have recently reported that gene transfer of calcitonin gene-related peptide in vivo to rabbits prevented constriction of the basilar artery in vivo after experimental subarachnoid hemorrhage, both when the vius was applied before and after hemorrhage. Here, we demonstrate results of this study, and discuss the possibility of gene therapy for stroke.

Details

Title: Subtitle: Gene therapy for vasospasm after subarachnoid hemorrhage
Creators: Kazunori Toyoda
Hiroaki Ooboshi
Hiroshi Nakane
Setsuro Ibayashi
Masatoshi Fujishima
Toshihiro Ueda
Donald D. Heistad - Humanities Iowa
Resource Type: Journal article
Publication Details: Nōsotchū, Vol.22(3), pp.468-471
DOI: 10.3995/jstroke.22.468
ISSN: 0912-0726
eISSN: 1883-1923
Language: Japanese
Date published: 2000
Academic Unit: Cardiovascular Medicine; Neuroscience and Pharmacology; Internal Medicine
Record Identifier: 9984304750002771

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