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Generalized tetanus despite prior vaccination and a protective level of anti-tetanus antibodies
Journal article   Peer reviewed

Generalized tetanus despite prior vaccination and a protective level of anti-tetanus antibodies

Daniel J Livorsi, Molly Eaton and Jonathan Glass
The American journal of the medical sciences, Vol.339(2), pp.200-201
02/2010
DOI: 10.1097/MAJ.0b013e3181c2f534
PMID: 20019579

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Abstract

Because of the success of widespread vaccination, tetanus rarely occurs in developed countries such as the United States. Vaccination, however, is not entirely protective even if patients develop an adequate antibody response. We discuss a case of generalized tetanus in an individual with both a history of prior vaccination and a measurable level of anti-tetanus antibodies at the time of presentation. We speculate that the patient's preexisting antibodies may have moderated his course of illness.
Humans Tetanus - prevention & control Male Anti-Bacterial Agents - therapeutic use Metronidazole - therapeutic use Adult Antibodies - blood Immunoglobulins - therapeutic use Benzodiazepines - therapeutic use Tetanus - pathology Tetanus Toxoid - immunology Muscle Relaxants, Central - therapeutic use Baclofen - therapeutic use

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