Journal article
Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion
Stem cell research, Vol.59, p.102636
03/2022
DOI: 10.1016/j.scr.2021.102636
PMCID: PMC9209596
PMID: 34953327
Abstract
16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers.
Details
- Title: Subtitle
- Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion
- Creators
- Deniz A Madencioglu - University of IowaKarina Kruth - University of IowaMallory Shin - University of IowaNancy Andreasen - University of IowaThomas Wassink - University of IowaAislinn Williams - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Stem cell research, Vol.59, p.102636
- DOI
- 10.1016/j.scr.2021.102636
- PMID
- 34953327
- PMCID
- PMC9209596
- NLM abbreviation
- Stem Cell Res
- ISSN
- 1873-5061
- eISSN
- 1876-7753
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 03/2022
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984203957602771
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