Journal article
Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension
Stem cell research, Vol.72, pp.103218-103218
10/01/2023
DOI: 10.1016/j.scr.2023.103218
PMCID: PMC11006094
PMID: 37804546
Abstract
Idiopathic pulmonary arterial hypertension (IPAH) is a rare disease, with an estimated 500-1000 new cases diagnosed every year. A portion of these cases may be caused by mutations in the BMPR2 gene, suggesting a possible genetic component in the development of the disease. Here, we report two human induced pluripotent stem cell (iPSC) lines generated from IPAH patients. Both cell lines provide valuable insight into the molecular and cellular mechanisms of IPAH and can be used to further understand the disease.
Details
- Title: Subtitle
- Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension
- Creators
- Gaoxian Chen - Stanford University School of MedicineLorena Orozco - Stanford University School of MedicineSophia Parmisano - Stanford University School of MedicineJames W. S. Jahng - Stanford University School of MedicineCarlos D. Vera - Stanford University School of MedicineYan Zhuge - Stanford University School of MedicineJoseph C. Wu - Stanford University School of MedicineDetlef Obal - Stanford University School of Medicine
- Resource Type
- Journal article
- Publication Details
- Stem cell research, Vol.72, pp.103218-103218
- DOI
- 10.1016/j.scr.2023.103218
- PMID
- 37804546
- PMCID
- PMC11006094
- NLM abbreviation
- Stem Cell Res
- ISSN
- 1873-5061
- eISSN
- 1876-7753
- Publisher
- Elsevier
- Number of pages
- 5
- Grant note
- MHCRI TIP grant, Stanford University; Stanford University 75N92020D00019; R01 HL126527; P01 HL141084 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 10/01/2023
- Academic Unit
- Anesthesia
- Record Identifier
- 9984696582002771
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