Journal article
Generic Health-Related Quality of Life in Patients Seeking Care for Pelvic Organ Prolapse
Female pelvic medicine & reconstructive surgery, Vol.27(6), pp.337-343
06/01/2021
DOI: 10.1097/SPV.0000000000001069
PMCID: PMC9039983
PMID: 34080581
Abstract
Objective
Using the American Urogynecologic Society multicenter Pelvic Floor Disorder Registry for Research, we (1) compared generic quality of life (QOL) in women planning pelvic organ prolapse (POP) treatment (surgery vs pessary), (2) correlated generic and condition-specific QOL scores, and (3) identified associations between generic QOL and other factors. Methods
This cross-sectional analysis assessed generic physical and mental QOL using the Patient-Reported Outcomes Measurement Information System Global Health Scale at baseline. Global Physical and Mental T-scores center on a representative US population sample (mean [SD], 50 [10]; higher scores, better health). Condition-specific QOL was assessed with Pelvic Floor Distress Inventory, Pelvic Floor Impact Questionnaire, and POP/Urinary Incontinence Sexual Function Questionnaire. Linear regression models identified associations between clinical factors and Global Physical/Mental scores. Results
Five hundred sixty-eight women (419 surgery, 149 pessary) were included. Surgery patients were younger, heavier, and more often sexually active (all P's <= 0.01). Global Physical scores were lower in the surgery versus pessary group, but not likely clinically meaningful (mean [SD], 48.8 [8.1] vs 50.4 [8.5]; P = 0.035); Global Mental scores were similar (51.4 [8.4] vs 51.9 [9.5], P = 0.56). Global Health scores correlated with Pelvic Floor Distress Inventory, Pelvic Floor Impact Questionnaire, and POP/Urinary Incontinence Sexual Function Questionnaire scores (all P's < 0.0001). In multivariable models, menopause was associated with better physical QOL, and constipation, coronary artery disease, pelvic pain, and increased body mass index with worse physical QOL. Age was associated with better mental QOL, and constipation, fecal incontinence, pelvic pain, and coronary artery disease with worse mental QOL. Conclusions
Women choosing POP surgery versus pessary had similar physical and mental generic QOL.
Details
- Title: Subtitle
- Generic Health-Related Quality of Life in Patients Seeking Care for Pelvic Organ Prolapse
- Creators
- Catherine S. Bradley - Roy J. and Lucille A. Carver College of MedicineHeidi W. Brown - University of Wisconsin–MadisonStuart S. Shippey - Riverside Regional Medical CenterRobert E. Gutman - MedStar Georgetown University HospitalUduak U. Andy - University of PennsylvaniaLadin A. Yurteri-Kaplan - Columbia University Medical CenterBela Kudish - University of Central FloridaAllen Mehr - Tripler Army Medical CenterAmy O'Boyle - Providence Med Grp, Olympia, WA USARaymond T. Foster - University of MissouriJennifer T. Anger - Cedars-Sinai Medical CenterPatrick Ten Eyck - Univ Iowa, Inst Clin & Translat Sci, Iowa City, IA USAPamela A. Moalli - Magee-Womens Research InstitutePelvic Floor Disorders Registry
- Resource Type
- Journal article
- Publication Details
- Female pelvic medicine & reconstructive surgery, Vol.27(6), pp.337-343
- DOI
- 10.1097/SPV.0000000000001069
- PMID
- 34080581
- PMCID
- PMC9039983
- NLM abbreviation
- Female Pelvic Med Reconstr Surg
- ISSN
- 2151-8378
- eISSN
- 2154-4212
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 7
- Grant note
- American Urogynecologic Society UL1TR002537 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA University of Iowa Institute for Clinical and Translational Science Boston Scientific 2017-2019; Boston Scientific
- Language
- English
- Date published
- 06/01/2021
- Academic Unit
- Epidemiology; Biostatistics; Obstetrics and Gynecology; Urology
- Record Identifier
- 9984315562402771
Metrics
13 Record Views