Journal article
Genetic and epigenetic studies in non-syndromic oral clefts
Oral diseases, Vol.28(5), pp.1339-1350
02/27/2022
DOI: 10.1111/odi.14146
PMID: 35122708
Abstract
The etiology of non-syndromic oral clefts (NSOFC) is complex with genetics, genomics, epigenetics, and stochastics factors playing a role. Several approaches have been applied to understand the etiology of non-syndromic oral clefts. These include linkage, candidate gene association studies, genome-wide association studies, whole-genome sequencing, copy number variations, and epigenetics. In this review, we shared these approaches, genes, and loci reported in some studies.
Details
- Title: Subtitle
- Genetic and epigenetic studies in non-syndromic oral clefts
- Creators
- Azeez Alade - University of IowaWaheed Awotoye - University of IowaAzeez Butali - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Oral diseases, Vol.28(5), pp.1339-1350
- DOI
- 10.1111/odi.14146
- PMID
- 35122708
- NLM abbreviation
- Oral Dis
- ISSN
- 1354-523X
- eISSN
- 1601-0825
- Publisher
- Wiley
- Number of pages
- 12
- Grant note
- DE028300 / National Institute of Dental and Craniofacial Research; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Dental & Craniofacial Research (NIDCR)
- Language
- English
- Date published
- 02/27/2022
- Academic Unit
- Oral Pathology, Radiology and Medicine; Stead Family Department of Pediatrics; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984353936402771
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