Journal article
Genetic influences on bipolar EEG power spectra
International journal of psychophysiology, Vol.65(1), pp.2-9
2007
DOI: 10.1016/j.ijpsycho.2007.02.004
PMID: 17383039
Abstract
The EEG bipolar power spectra provide more localization than spectral measures obtained from monopolar referencing strategies, and have been shown to be useful endophenotypes of psychiatric disorders such as alcoholism. We estimated the additive genetic heritability of resting bipolar EEG power spectra in a large sample of non-twin sibling pairs. The corresponding heritabilities ranged between 0.220 and 0.647 and were highly significant at all 38 electrode pairs for theta (3–7 Hz), low-alpha (7–9 Hz), high-alpha (9–12 Hz), low-beta (12–16 Hz), middle-beta (16–20 Hz) and high-beta (20–28 Hz) frequency bands. The heritabilities were the highest in the high-alpha and low-beta bands at most electrode pairs. The heritabilities were most variable across the head in the three beta bands. Other heritability patterns were also identified within each frequency band. Our results suggest that substantial proportions of the variability in the bipolar EEG measures are explained by genetic factors.
Details
- Title: Subtitle
- Genetic influences on bipolar EEG power spectra
- Creators
- Yongqiang Tang - Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USADavid B Chorlian - Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USAMadhavi Rangaswamy - Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USABernice Porjesz - Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USALance Bauer - University of Connecticut Farmington, CT, USASamuel Kuperman - University of Iowa Psychiatry Research, Iowa City, IA, USASean O'Connor - Indiana University School of Medicine, Indianapolis, IN, USAJohn Rohrbaugh - Washington University School of Medicine, St. Louis, MO, USAMarc Schuckit - University of California at San Diego, San Diego, CA, USAArthur Stimus - Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USAHenri Begleiter - Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USA
- Resource Type
- Journal article
- Publication Details
- International journal of psychophysiology, Vol.65(1), pp.2-9
- Publisher
- Elsevier B.V
- DOI
- 10.1016/j.ijpsycho.2007.02.004
- PMID
- 17383039
- ISSN
- 0167-8760
- eISSN
- 1872-7697
- Language
- English
- Date published
- 2007
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984003432802771
Metrics
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