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Genetic testing for age-related macular degeneration: not indicated now
Journal article   Peer reviewed

Genetic testing for age-related macular degeneration: not indicated now

Edwin M Stone
JAMA ophthalmology, Vol.133(5), pp.598-600
05/2015
DOI: 10.1001/jamaophthalmol.2015.0369
PMID: 25789813

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Abstract

Age-related macular degeneration is a very common condition that is caused by a complex interplay of genetic and environmental factors. It is likely that, in the future, genetic testing will allow physicians to achieve better clinical outcomes by administering specific treatments to patients based on their genotypes. However, improved outcomes for genotyped patients have not yet been demonstrated in a prospective clinical trial, and as a result, the costs and risks of routine genetic testing currently outweigh the benefits for patients with age-related macular degeneration.
Academies and Institutes Genetic Predisposition to Disease Genetic Testing Prospective Studies Risk Assessment Humans Proteins - genetics Macular Degeneration - genetics Ophthalmology - organization & administration Aged, 80 and over Aged Complement Factor H - genetics Practice Guidelines as Topic

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