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Genetics and genomics etiology of nonsyndromic orofacial clefts
Journal article   Open access   Peer reviewed

Genetics and genomics etiology of nonsyndromic orofacial clefts

Wasiu L Adeyemo and Azeez Butali
Molecular genetics & genomic medicine, Vol.5(1), pp.3-7
01/2017
DOI: 10.1002/mgg3.272
PMCID: PMC5241211
PMID: 28116324
url
https://doi.org/10.1002/mgg3.272View
Published (Version of record) Open Access

Abstract

Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools.

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