Journal article
Genetics of Primate Lymphomas in a Baboon (Papio-Hamadryas) Colony of Sukhumi, Ussr
Genetica, Vol.73(1-2), pp.145-157
08/31/1987
DOI: 10.1007/BF00057445
Abstract
A lymphoma outbreak occurred at the Sukhumi Center in the Late 1960's, when 12 baboons were inoculated with blood from human leukemia patients. Out of a total of 3219 animals, 218 contracted lymphoma and died. This outbreak appears to be primarily horizontal in transmission. Genetic investigations reveal that: (1) inbreeding does not increase risk of lymphoma; (2) there is a weak association between the PGM2 locus and lymphoma; (3) based upon path analysis, there is evidence of a significant transmissible component (genetic predisposition) passed from the parental to the next generation.
Details
- Title: Subtitle
- Genetics of Primate Lymphomas in a Baboon (Papio-Hamadryas) Colony of Sukhumi, Ussr
- Creators
- M. H. CrawfordE J Devor - University of IowaD. H. OrourkeL. A. YakovlevaA. F. VoevodinB. A. Lapin
- Resource Type
- Journal article
- Publication Details
- Genetica, Vol.73(1-2), pp.145-157
- DOI
- 10.1007/BF00057445
- ISSN
- 0016-6707
- Language
- English
- Date published
- 08/31/1987
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9983557120602771
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