Journal article
Genetics of Sarcoidosis
Clinics in chest medicine, Vol.36(4), pp.569-584
12/2015
DOI: 10.1016/j.ccm.2015.08.002
PMID: 26593134
Abstract
Sarcoidosis is a disease with highly variable presentation and progression; although it is hypothesized that disease phenotype is related to genetic variation, how much of this variability is driven by genetic factors is not known. The HLA region is the most strongly and consistently associated genetic risk factor for sarcoidosis, supporting the notion that sarcoidosis is an exposure-mediated immunologic disease. Most of the genetic etiology of sarcoidosis remains unknown in terms of the specific variants that increase risk in various populations, their biologic functions, and how they interact with environmental exposures.
Details
- Title: Subtitle
- Genetics of Sarcoidosis
- Creators
- Tasha E Fingerlin - National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USANabeel Hamzeh - Division of Environmental Occupational Health and Sciences, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USALisa A Maier - Division of Environmental Occupational Health and Sciences, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA
- Resource Type
- Journal article
- Publication Details
- Clinics in chest medicine, Vol.36(4), pp.569-584
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.ccm.2015.08.002
- PMID
- 26593134
- ISSN
- 0272-5231
- eISSN
- 1557-8216
- Language
- English
- Date published
- 12/2015
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
- Record Identifier
- 9984094519202771
Metrics
13 Record Views