Journal article
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nature genetics, Vol.51(5), pp.793-803
05/2019
DOI: 10.1038/s41588-019-0397-8
PMCID: PMC6956732
PMID: 31043756
Abstract
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P < 1 × 10
Details
- Title: Subtitle
- Genome-wide association study identifies 30 loci associated with bipolar disorder
- Creators
- Eli A Stahl - Medical and Population Genetics, Broad Institute, Cambridge, MA, USA. eli.stahl@mssm.eduGerome Breen - NIHR BRC for Mental Health, King's College London, London, UKAndreas J Forstner - Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, SwitzerlandAndrew McQuillin - Division of Psychiatry, University College London, London, UKStephan Ripke - Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USAVassily Trubetskoy - Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, GermanyManuel Mattheisen - iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, DenmarkYunpeng Wang - Institute of Clinical Medicine, University of Oslo, Oslo, NorwayJonathan R I Coleman - NIHR BRC for Mental Health, King's College London, London, UKHéléna A Gaspar - NIHR BRC for Mental Health, King's College London, London, UKChristiaan A de Leeuw - Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the NetherlandsStacy Steinberg - deCODE Genetics/Amgen, Reykjavik, IcelandJennifer M Whitehead Pavlides - Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, AustraliaMaciej Trzaskowski - Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, AustraliaEnda M Byrne - Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, AustraliaTune H Pers - Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USAPeter A Holmans - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandAlexander L Richards - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandLiam Abbott - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USAEsben Agerbo - National Centre for Register-based Research and Centre for Integrated Register-based Research, Aarhus University, Aarhus, DenmarkHuda Akil - Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, USADiego Albani - Department of Neuroscience, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milan, ItalyNey Alliey-Rodriguez - Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USAThomas D Als - iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, DenmarkAdebayo Anjorin - Department of Psychiatry, Berkshire Healthcare NHS Foundation Trust, Bracknell, UKVerneri Antilla - Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USASwapnil Awasthi - Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, GermanyJudith A Badner - Department of Psychiatry, Rush University Medical Center, Chicago, IL, USAMarie Bækvad-Hansen - Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, DenmarkJack D Barchas - Department of Psychiatry, Weill Cornell Medical College, New York, NY, USANicholas Bass - Division of Psychiatry, University College London, London, UKMichael Bauer - Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyRichard Belliveau - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USASarah E Bergen - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenCarsten Bøcker Pedersen - National Centre for Register-based Research and Centre for Integrated Register-based Research, Aarhus University, Aarhus, DenmarkErlend Bøen - Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, NorwayMarco P Boks - Psychiatry, UMC Utrecht Brain Center Rudolf Magnus, Utrecht, the NetherlandsJames Boocock - Human Genetics, University of California, Los Angeles, Los Angeles, CA, USAMonika Budde - Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich, GermanyWilliam Bunney - Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USAMargit Burmeister - Molecular & Behavioral Neuroscience Institute and Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USAJonas Bybjerg-Grauholm - Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, DenmarkWilliam Byerley - Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USAMiquel Casas - Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut, Universitat Autònoma de Barcelona, Barcelona, SpainFelecia Cerrato - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USAPablo Cervantes - Department of Psychiatry, Mood Disorders Program, McGill University Health Center, Montreal, Quebec, CanadaKimberly Chambert - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USAAlexander W Charney - Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USADanfeng Chen - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USAClaire Churchhouse - Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USAToni-Kim Clarke - Division of Psychiatry, University of Edinburgh, Edinburgh, ScotlandWilliam Coryell - University of Iowa Hospitals and Clinics, Iowa City, IA, USADavid W Craig - Translational Genomics, USC, Phoenix, AZ, USACristiana Cruceanu - Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, GermanyDavid Curtis - UCL Genetics Institute, University College London, London, UKPiotr M Czerski - Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, PolandAnders M Dale - Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USASimone de Jong - NIHR BRC for Mental Health, King's College London, London, UKFranziska Degenhardt - Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, GermanyJurgen Del-Favero - Applied Molecular Genomics Unit, VIB Department of Molecular Genetics, University of Antwerp, Antwerp, BelgiumJ Raymond DePaulo - Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USASrdjan Djurovic - NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, NorwayAmanda L Dobbyn - Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USAAshley Dumont - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USATorbjørn Elvsåshagen - NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, NorwayValentina Escott-Price - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandChun Chieh Fan - Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USASascha B Fischer - Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, SwitzerlandMatthew Flickinger - Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USATatiana M Foroud - Department of Medical & Molecular Genetics, Indiana University, Indianapolis, IN, USALiz Forty - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandJosef Frank - Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GermanyChristine Fraser - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandNelson B Freimer - Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USALouise Frisén - Child and Adolescent Psychiatry Research Center, Stockholm, SwedenKatrin Gade - Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, GermanyDiane Gage - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USAJulie Garnham - Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, CanadaClaudia Giambartolomei - Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USAMarianne Giørtz Pedersen - National Centre for Register-based Research and Centre for Integrated Register-based Research, Aarhus University, Aarhus, DenmarkJaqueline Goldstein - Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USAScott D Gordon - Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, AustraliaKatherine Gordon-Smith - Department of Psychological Medicine, University of Worcester, Worcester, UKElaine K Green - School of Biomedical Sciences, Plymouth University Peninsula Schools of Medicine and Dentistry, University of Plymouth, Plymouth, UKMelissa J Green - Neuroscience Research Australia, Sydney, New South Wales, AustraliaTiffany A Greenwood - Department of Psychiatry, University of California, San Diego, La Jolla, CA, USAJakob Grove - Bioinformatics Research Centre, Aarhus University, Aarhus, DenmarkWeihua Guan - Biostatistics, University of Minnesota System, Minneapolis, MN, USAJosé Guzman-Parra - Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, SpainMarian L Hamshere - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandMartin Hautzinger - Department of Psychology, Eberhard Karls Universität Tübingen, Tubingen, GermanyUrs Heilbronner - Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich, GermanyStefan Herms - Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, SwitzerlandMaria Hipolito - Department of Psychiatry and Behavioral Sciences, Howard University Hospital, Washington, DC, USAPer Hoffmann - Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, SwitzerlandDominic Holland - Center for Multimodal Imaging and Genetics, University of California, San Diego, La Jolla, CA, USALaura Huckins - Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USAStéphane Jamain - Faculté de Médecine, Université Paris Est, Créteil, FranceJessica S Johnson - Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USAAnders Juréus - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenRadhika Kandaswamy - MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UKRobert Karlsson - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenJames L Kennedy - Institute of Medical Sciences, University of Toronto, Toronto, Ontario, CanadaSarah Kittel-Schneider - Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, GermanyJames A Knowles - Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USAManolis Kogevinas - ISGlobal, Barcelona, SpainAnna C Koller - Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, GermanyRalph Kupka - Psychiatry, VU Medisch Centrum, Amsterdam, the NetherlandsCatharina Lavebratt - Department of Molecular Medicine and Surgery, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, SwedenJacob Lawrence - Department of, rth East London NHS Foundation Trust, Ilford, UKWilliam B Lawson - Department of Psychiatry and Behavioral Sciences, Howard University Hospital, Washington, DC, USAMarkus Leber - Department of Neurodegenerative Diseases and Geropsychiatry, University Hospital Bonn, Bonn, GermanyPhil H Lee - Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USAShawn E Levy - HudsonAlpha Institute for Biotechnology, Huntsville, AL, USAJun Z Li - Department of Human Genetics, University of Michigan, Ann Arbor, MI, USAChunyu Liu - Department of Psychiatry, University of Illinois at Chicago College of Medicine, Chicago, IL, USASusanne Lucae - Max Planck Institute of Psychiatry, Munich, GermanyAnna Maaser - Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, GermanyDonald J MacIntyre - Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UKPamela B Mahon - Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USAWolfgang Maier - Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, GermanyLina Martinsson - Department of Clinical Neuroscience, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, SwedenSteve McCarroll - Department of Genetics, Harvard Medical School, Boston, MA, USAPeter McGuffin - MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UKMelvin G McInnis - Department of Psychiatry, University of Michigan, Ann Arbor, MI, USAJames D McKay - Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, FranceHelena Medeiros - Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USASarah E Medland - Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, AustraliaFan Meng - Department of Psychiatry, University of Michigan, Ann Arbor, MI, USALili Milani - Estonian Genome Center, University of Tartu, Tartu, EstoniaGrant W Montgomery - Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, AustraliaDerek W Morris - Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, IrelandThomas W Mühleisen - Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, GermanyNiamh Mullins - MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UKHoang Nguyen - Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USACaroline M Nievergelt - Research/Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, CA, USAAnnelie Nordin Adolfsson - Department of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, SwedenEvaristus A Nwulia - Department of Psychiatry and Behavioral Sciences, Howard University Hospital, Washington, DC, USAClaire O'Donovan - Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, CanadaLoes M Olde Loohuis - Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USAAnil P S Ori - Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USALilijana Oruc - Department of Clinical Psychiatry, Psychiatry Clinic, Clinical Center University of Sarajevo, Sarajevo, Bosnia and HerzegovinaUrban Ösby - Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, SwedenRoy H Perlis - Division of Clinical Research, Massachusetts General Hospital, Boston, MA, USAAmy Perry - Department of Psychological Medicine, University of Worcester, Worcester, UKAndrea Pfennig - Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyJames B Potash - Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USAShaun M Purcell - Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USAEline J Regeer - Outpatient Clinic for Bipolar Disorder, Altrecht, Utrecht, the NetherlandsAndreas Reif - Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, GermanyCéline S Reinbold - Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, SwitzerlandJohn P Rice - Department of Psychiatry, Washington University in Saint Louis, Saint Louis, MO, USAFabio Rivas - Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, SpainMargarita Rivera - Department of Biochemistry and Molecular Biology II, Institute of Neurosciences, Center for Biomedical Research, University of Granada, Granada, SpainPanos Roussos - Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USADouglas M Ruderfer - Medicine, Psychiatry, Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USAEuijung Ryu - Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USACristina Sánchez-Mora - Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut, Universitat Autònoma de Barcelona, Barcelona, SpainAlan F Schatzberg - Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USAWilliam A Scheftner - Rush University Medical Center, Chicago, IL, USANicholas J Schork - Scripps Translational Science Institute, La Jolla, CA, USACynthia Shannon Weickert - Neuroscience Research Australia, Sydney, New South Wales, AustraliaTatyana Shehktman - Department of Psychiatry, University of California, San Diego, La Jolla, CA, USAPaul D Shilling - Department of Psychiatry, University of California, San Diego, La Jolla, CA, USAEngilbert Sigurdsson - Faculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, IcelandClaire Slaney - Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, CanadaOlav B Smeland - NORMENT, University of Oslo, Oslo, NorwayJanet L Sobell - Psychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, CA, USAChristine Søholm Hansen - Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, DenmarkAnne T Spijker - Mood Disorders, PsyQ, Rotterdam, the NetherlandsDavid St Clair - Institute for Medical Sciences, University of Aberdeen, Aberdeen, UKMichael Steffens - Research Division, Federal Institute for Drugs and Medical Devices (BfArM), Bonn, GermanyJohn S Strauss - Centre for Addiction and Mental Health, Toronto, Onatario, CanadaFabian Streit - Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GermanyJana Strohmaier - Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GermanySzabolcs Szelinger - Neurogenomics, TGen, Phoenix, AZ, USARobert C Thompson - Department of Psychiatry, University of Michigan, Ann Arbor, MI, USAThorgeir E Thorgeirsson - deCODE Genetics/Amgen, Reykjavik, IcelandJens Treutlein - Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GermanyHelmut Vedder - Department of Psychiatry, Psychiatrisches Zentrum Nordbaden, Wiesloch, GermanyWeiqing Wang - Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USAStanley J Watson - Department of Psychiatry, University of Michigan, Ann Arbor, MI, USAThomas W Weickert - Neuroscience Research Australia, Sydney, New South Wales, AustraliaStephanie H Witt - Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GermanySimon Xi - Computational Sciences Center of Emphasis, Pfizer Global Research and Development, Cambridge, MA, USAWei Xu - Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, CanadaAllan H Young - Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UKPeter Zandi - Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USAPeng Zhang - Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USASebastian Zöllner - Department of Psychiatry, University of Michigan, Ann Arbor, MI, USARolf Adolfsson - Department of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, SwedenIngrid Agartz - NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Institute of Clinical Medicine and Diakonhjemmet Hospital, University of Oslo, Oslo, NorwayMartin Alda - National Institute of Mental Health, Klecany, Czech RepublicLena Backlund - Department of Clinical Neuroscience, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, SwedenBernhard T Baune - Department of Psychiatry, University of Munster, Munster, GermanyFrank Bellivier - Department of Psychiatry, Université Paris Diderot, Paris, FranceWade H Berrettini - Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USAJoanna M Biernacka - Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USADouglas H R Blackwood - Division of Psychiatry, University of Edinburgh, Edinburgh, ScotlandMichael Boehnke - Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USAAnders D Børglum - iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, DenmarkAiden Corvin - Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, IrelandNicholas Craddock - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandMark J Daly - Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USAUdo Dannlowski - Department of Psychiatry, University of Munster, Munster, GermanyTõnu Esko - Division of Endocrinology, Children's Hospital Boston, Boston, MA, USABruno Etain - Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, London, UKMark Frye - Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USAJanice M Fullerton - School of Medical Sciences, University of New South Wales, Sydney, New South Wales, AustraliaElliot S Gershon - Department of Human Genetics, University of Chicago, Chicago, IL, USAMichael Gill - Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, IrelandFernando Goes - Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USAMaria Grigoroiu-Serbanescu - Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, RomaniaJoanna Hauser - Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, PolandDavid M Hougaard - Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, DenmarkChristina M Hultman - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenIan Jones - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandLisa A Jones - Department of Psychological Medicine, University of Worcester, Worcester, UKRené S Kahn - Psychiatry, UMC Utrecht Brain Center Rudolf Magnus, Utrecht, the NetherlandsGeorge Kirov - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandMikael Landén - Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, SwedenMarion Leboyer - INSERM, Paris, FranceCathryn M Lewis - Department of Medical & Molecular Genetics, King's College London, London, UKQingqin S Li - Neuroscience Therapeutic Area, Janssen Research and Development, LLC, Titusville, NJ, USAJolanta Lissowska - Cancer Epidemiology and Prevention, M. Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, PolandNicholas G Martin - School of Psychology, The University of Queensland, Brisbane, Queensland, AustraliaFermin Mayoral - Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, SpainSusan L McElroy - Research Institute, Lindner Center of HOPE, Mason, OH, USAAndrew M McIntosh - Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UKFrancis J McMahon - Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USAIngrid Melle - Division of Mental Health and Addiction and Institute of Clinical Medicine, Oslo University Hospital and University of Oslo, Oslo, NorwayAndres Metspalu - Institute of Molecular and Cell Biology, University of Tartu, Tartu, EstoniaPhilip B Mitchell - School of Psychiatry, University of New South Wales, Sydney, New South Wales, AustraliaGunnar Morken - Department of Psychiatry, St Olavs University Hospital, Trondheim, NorwayOle Mors - Psychosis Research Unit, Aarhus University Hospital, Risskov, DenmarkPreben Bo Mortensen - National Centre for Register-based Research and Centre for Integrated Register-based Research, Aarhus University, Aarhus, DenmarkBertram Müller-Myhsok - University of Liverpool, Liverpool, UKRichard M Myers - HudsonAlpha Institute for Biotechnology, Huntsville, AL, USABenjamin M Neale - Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USAVishwajit Nimgaonkar - Psychiatry and Human Genetics, University of Pittsburgh, Pittsburgh, PA, USAMerete Nordentoft - Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, DenmarkMarkus M Nöthen - Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, GermanyMichael C O'Donovan - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandKetil J Oedegaard - Faculty of Medicine and Dentistry, University of Bergen, Bergen, NorwayMichael J Owen - Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, EnglandSara A Paciga - Human Genetics and Computational Biomedicine, Pfizer Global Research and Development, Groton, CT, USACarlos Pato - College of Medicine Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USAMichele T Pato - Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USADanielle Posthuma - Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the NetherlandsJosep Antoni Ramos-Quiroga - Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut, Universitat Autònoma de Barcelona, Barcelona, SpainMarta Ribasés - Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut, Universitat Autònoma de Barcelona, Barcelona, SpainMarcella Rietschel - Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GermanyGuy A Rouleau - Montreal Neurological Institute and Hospital, Montreal, Quebec, CanadaMartin Schalling - Department of Molecular Medicine and Surgery, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, SwedenPeter R Schofield - School of Medical Sciences, University of New South Wales, Sydney, New South Wales, AustraliaThomas G Schulze - Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USAAlessandro Serretti - Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, ItalyJordan W Smoller - Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USAHreinn Stefansson - deCODE Genetics/Amgen, Reykjavik, IcelandKari Stefansson - Faculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, IcelandEystein Stordal - Department of Mental Health, Norwegian University of Science and Technology, Trondheim, NorwayPatrick F Sullivan - Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAGustavo Turecki - Department of Psychiatry, McGill University, Montreal, Quebec, CanadaArne E Vaaler - Department of Psychiatry, Sankt Olavs Hospital Universitetssykehuset i Trondheim, Trondheim, NorwayEduard Vieta - Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, SpainJohn B Vincent - Centre for Addiction and Mental Health, Toronto, Onatario, CanadaThomas Werge - Department of Clinical Medicine, University of Copenhagen, Copenhagen, DenmarkJohn I Nurnberger - Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USANaomi R Wray - Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, AustraliaArianna Di Florio - Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAHoward J Edenberg - Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USASven Cichon - Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, GermanyRoel A Ophoff - Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USALaura J Scott - Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USAOle A Andreassen - NORMENT, University of Oslo, Oslo, NorwayJohn Kelsoe - Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. jkelsoe@ucsd.eduPamela Sklar - Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USAeQTLGen Consortium
- Resource Type
- Journal article
- Publication Details
- Nature genetics, Vol.51(5), pp.793-803
- Publisher
- United States
- DOI
- 10.1038/s41588-019-0397-8
- PMID
- 31043756
- PMCID
- PMC6956732
- ISSN
- 1546-1718
- eISSN
- 1546-1718
- Grant note
- MR/L010305/1 / Medical Research Council Wellcome Trust U01 MH109514 / NIMH NIH HHS U01 MH109536 / NIMH NIH HHS R00 MH101367 / NIMH NIH HHS
- Language
- English
- Date published
- 05/2019
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003971602771
Metrics
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