Journal article
Genome-wide linkage analysis of blood pressure under locus heterogeneity
BMC genetics, Vol.4(Suppl 1), pp.S78-S78
2003
DOI: 10.1186/1471-2156-4-S1-S78
PMCID: PMC1866517
PMID: 14975146
Abstract
We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the Framingham Heart Study. Evidence of linkage was found on four markers (GATA89G08, GATA23D06, GATA14E09, and 049xd2) at a significance level of 0.01. Two of them (GATA14E09 and 049xd2) seem to overlap with linkage signals reported previously, while the other two are not linked to any known signals.
Details
- Title: Subtitle
- Genome-wide linkage analysis of blood pressure under locus heterogeneity
- Creators
- Xinqun Yang - Department of Psychiatry, The University of Iowa, Iowa City, USAKai Wang - Department of Psychiatry, The University of Iowa, Iowa City, USAJian Huang - Department of Psychiatry, The University of Iowa, Iowa City, USAVeronica J Vieland - Department of Psychiatry, The University of Iowa, Iowa City, USA
- Resource Type
- Journal article
- Publication Details
- BMC genetics, Vol.4(Suppl 1), pp.S78-S78
- DOI
- 10.1186/1471-2156-4-S1-S78
- PMID
- 14975146
- PMCID
- PMC1866517
- NLM abbreviation
- BMC Genet
- ISSN
- 1471-2156
- eISSN
- 1471-2156
- Publisher
- BioMed Central; London
- Language
- English
- Date published
- 2003
- Academic Unit
- Statistics and Actuarial Science; Biostatistics
- Record Identifier
- 9983997477902771
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