Genome-wide linkage and follow-up association study of postpartum mood symptoms

Pamela Belmonte Mahon; Jennifer L Payne; Dean F MacKinnon; Francis M Mondimore; Fernando S Goes; Barbara Schweizer; Dubravka Jancic; William H Coryell; Peter A Holmans; Jianxin Shi; James A Knowles; William A Scheftner; Myrna M Weissman; Douglas F Levinson; J Raymond Depaulo Jr; Peter P Zandi; James B Potash; Bipolar Disorder Genome Study (BiGS) Consortium

doi:10.1176/appi.ajp.2009.09030417

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Genome-wide linkage and follow-up association study of postpartum mood symptoms

Journal article

Peer reviewed

Genome-wide linkage and follow-up association study of postpartum mood symptoms

Pamela Belmonte Mahon, Jennifer L Payne, Dean F MacKinnon, Francis M Mondimore, Fernando S Goes, Barbara Schweizer, Dubravka Jancic, William H Coryell, Peter A Holmans, Jianxin Shi, …

The American journal of psychiatry, Vol.166(11), pp.1229-1237

11/2009

DOI: 10.1176/appi.ajp.2009.09030417

PMCID: PMC3665341

PMID: 19755578

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Abstract

Family studies have suggested that postpartum mood symptoms might have a partly genetic etiology. The authors used a genome-wide linkage analysis to search for chromosomal regions that harbor genetic variants conferring susceptibility for such symptoms. The authors then fine-mapped their best linkage regions, assessing single nucleotide polymorphisms (SNPs) for genetic association with postpartum symptoms.

Pregnancy

Depression, Postpartum - genetics

Genetic Predisposition to Disease

Genome-Wide Association Study

Follow-Up Studies

Humans

Middle Aged

Genotype

Chromosome Mapping

Bipolar Disorder - diagnosis

Bipolar Disorder - genetics

Genetic Variation

Chromosomes, Human, Pair 9 - genetics

Depressive Disorder, Major - genetics

Pedigree

Polymorphism, Single Nucleotide - genetics

Adult

Depression, Postpartum - diagnosis

Female

Models, Genetic

Depressive Disorder, Major - diagnosis

Chromosomes, Human, Pair 1 - genetics

Microsatellite Repeats

Genetic Linkage

Details

Title: Subtitle: Genome-wide linkage and follow-up association study of postpartum mood symptoms
Creators: Pamela Belmonte Mahon - Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
Jennifer L Payne
Dean F MacKinnon
Francis M Mondimore
Fernando S Goes
Barbara Schweizer
Dubravka Jancic
William H Coryell
Peter A Holmans
Jianxin Shi
James A Knowles
William A Scheftner
Myrna M Weissman
Douglas F Levinson
J Raymond Depaulo Jr
Peter P Zandi
James B Potash
Bipolar Disorder Genome Study (BiGS) Consortium
Resource Type: Journal article
Publication Details: The American journal of psychiatry, Vol.166(11), pp.1229-1237
DOI: 10.1176/appi.ajp.2009.09030417
PMID: 19755578
PMCID: PMC3665341
NLM abbreviation: Am J Psychiatry
ISSN: 0002-953X
eISSN: 1535-7228
Publisher: United States
Grant note: R01MH059542 / NIMH NIH HHS R01 MH059535 / NIMH NIH HHS MH061675 / NIMH NIH HHS K23 MH074799-01A2 / NIMH NIH HHS R01 MH59553 / NIMH NIH HHS R01 MH059566 / NIMH NIH HHS MH59566 / NIMH NIH HHS R01 MH059542 / NIMH NIH HHS 5R01MH059542 / NIMH NIH HHS MH067257 / NIMH NIH HHS R01 MH59545 / NIMH NIH HHS R01 MH061686 / NIMH NIH HHS U01 MH46280 / NIMH NIH HHS 5R01MH059541 / NIMH NIH HHS R01MH60866 / NIMH NIH HHS R01 MH060866 / NIMH NIH HHS R01 MH059567 / NIMH NIH HHS R01 MH059587 / NIMH NIH HHS R01 MH059552 / NIMH NIH HHS Z01 MH002810 / Intramural NIH HHS U01 MH46282 / NIMH NIH HHS R01 MH059541-05 / NIMH NIH HHS R01 MH59567 / NIMH NIH HHS R01 MH059533 / NIMH NIH HHS U01 MH060879 / NIMH NIH HHS R01 MH059541 / NIMH NIH HHS Z01 MH002810-05 / Intramural NIH HHS R01 MH059565 / NIMH NIH HHS R01 MH59535 / NIMH NIH HHS R01 MH059571 / NIMH NIH HHS G0801418 / Medical Research Council MH59586 / NIMH NIH HHS K01 MH072866 / NIMH NIH HHS R01 MH060870 / NIMH NIH HHS R01 MH061675 / NIMH NIH HHS K23 MH074799 / NIMH NIH HHS R01 MH60068 / NIMH NIH HHS 1K24MH64197 / NIMH NIH HHS R01 MH067257 / NIMH NIH HHS R01 MH060879 / NIMH NIH HHS R01 MH060912 / NIMH NIH HHS 5R01MH060912 / NIMH NIH HHS N01HG65403 / NHGRI NIH HHS R01 MH059548 / NIMH NIH HHS MH059588 / NIMH NIH HHS 1Z01MH002810-01 / NIMH NIH HHS R01 MH059586 / NIMH NIH HHS R01 MH59533 / NIMH NIH HHS MH059565 / NIMH NIH HHS MH059571 / NIMH NIH HHS 1K23 MH074799 / NIMH NIH HHS 5R01MH059552 / NIMH NIH HHS R01 MH61686 / NIMH NIH HHS R01MH059552 / NIMH NIH HHS MH60870 / NIMH NIH HHS U01 MH46274 / NIMH NIH HHS R01 MH059556 / NIMH NIH HHS K01 MH072866-01 / NIMH NIH HHS MH59587 / NIMH NIH HHS R01 MH059545 / NIMH NIH HHS 5R01MH061686 / NIMH NIH HHS R01 MH059534 / NIMH NIH HHS R01 MH059588 / NIMH NIH HHS R01 MH059553 / NIMH NIH HHS K24 MH064197 / NIMH NIH HHS R01MH060866 / NIMH NIH HHS R01 MH060068 / NIMH NIH HHS
Language: English
Date published: 11/2009
Academic Unit: Psychiatry
Record Identifier: 9984003923302771

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