Genomic Analysis of Cardiac Surgery-Associated Mycobacterium chimaera Infections, United States

Nabeeh A Hasan; L Elaine Epperson; Adrian Lawsin; Rachael R Rodger; Kiran M Perkins; Alison Laufer Halpin; K Allison Perry; Heather Moulton-Meissner; Daniel J Diekema; Matthew B Crist; Joseph F Perz; Max Salfinger; Charles L Daley; Michael Strong

doi:10.3201/eid2503.181282

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Genomic Analysis of Cardiac Surgery-Associated Mycobacterium chimaera Infections, United States

Journal article

Open access

Peer reviewed

Genomic Analysis of Cardiac Surgery-Associated Mycobacterium chimaera Infections, United States

Nabeeh A Hasan, L Elaine Epperson, Adrian Lawsin, Rachael R Rodger, Kiran M Perkins, Alison Laufer Halpin, K Allison Perry, Heather Moulton-Meissner, Daniel J Diekema, Matthew B Crist, …

Emerging infectious diseases, Vol.25(3), pp.559-563

03/2019

DOI: 10.3201/eid2503.181282

PMCID: PMC6390774

PMID: 30789131

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Abstract

A surgical heater-cooler unit has been implicated as the source for Mycobacterium chimaera infections among cardiac surgery patients in several countries. We isolated M. chimaera from heater-cooler units and patient infections in the United States. Whole-genome sequencing corroborated a risk for these units acting as a reservoir for this pathogen.

Mycobacterium Infections - epidemiology

United States - epidemiology

Genome, Bacterial

Mycobacterium Infections - etiology

Surgical Wound Infection - epidemiology

Humans

Genotype

Cardiac Surgical Procedures - adverse effects

Mycobacterium - genetics

Mycobacterium - classification

Mycobacterium Infections - microbiology

Polymorphism, Single Nucleotide

Genomics - methods

Details

Title: Subtitle: Genomic Analysis of Cardiac Surgery-Associated Mycobacterium chimaera Infections, United States
Creators: Nabeeh A Hasan
L Elaine Epperson
Adrian Lawsin
Rachael R Rodger
Kiran M Perkins
Alison Laufer Halpin
K Allison Perry
Heather Moulton-Meissner
Daniel J Diekema
Matthew B Crist
Joseph F Perz
Max Salfinger
Charles L Daley
Michael Strong
Resource Type: Journal article
Publication Details: Emerging infectious diseases, Vol.25(3), pp.559-563
DOI: 10.3201/eid2503.181282
PMID: 30789131
PMCID: PMC6390774
NLM abbreviation: Emerg Infect Dis
ISSN: 1080-6059
eISSN: 1080-6059
Publisher: United States
Language: English
Date published: 03/2019
Academic Unit: Infectious Diseases; Pathology; Internal Medicine
Record Identifier: 9984001164402771

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