Journal article
Genomic characterization of HBV genotype F in Bolivia : genotype F subgenotypes correlate with geographic distribution and T1858 variant
Archives of virology, Vol.151(3), pp.589-597
2006
DOI: 10.1007/s00705-005-0671-1
PMID: 14328798
Abstract
Hepatitis B virus (HBV) strains were classified into eight genotypes from A to H. Genotype F, an indigenous genotype in Central and South America, has been classified into subgenotypes. An in-depth phylogenetic analysis was performed using two full-length Bolivian HBV sequences and other genotype F strains from the database. A novel nomenclature of subgenotypes of genotype F was proposed, in which Bolivia strains belonged to subgenotype F4. This subgenotype had both Leu45 and Ile110 in the S gene, and linked to the T1858 in the precore. This novel nomenclature demonstrated the relation between variability of the HBV genome and the restricted geographical distribution of the virus in some parts of Central and South America.
Details
- Title: Subtitle
- Genomic characterization of HBV genotype F in Bolivia : genotype F subgenotypes correlate with geographic distribution and T1858 variant
- Creators
- T. T. T HUY - Department of Pathology, National Institute of Infectious Diseases, Tokyo, JapanH USHIJIMA - Department of Developmental Medical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanT SATA - Department of Pathology, National Institute of Infectious Diseases, Tokyo, JapanK ABE - National Institute of Infectious Diseases
- Resource Type
- Journal article
- Publication Details
- Archives of virology, Vol.151(3), pp.589-597
- Publisher
- Springer
- DOI
- 10.1007/s00705-005-0671-1
- PMID
- 14328798
- ISSN
- 0304-8608
- eISSN
- 1432-8798
- Language
- English
- Date published
- 2006
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094350402771
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