Journal article
Geriatric Syndromes and Incident Disability in Older Women: Results from the Women's Health Initiative Observational Study
Journal of the American Geriatrics Society (JAGS), Vol.61(3), pp.371-379
03/01/2013
DOI: 10.1111/jgs.12147
PMCID: PMC3602348
PMID: 23452034
Abstract
Objectives To determine how the number of geriatric syndromes is associated with incident disability in community-based populations of older adults. Design Longitudinal analysis from the Women's Health Initiative Observational Study (WHI-OS). Setting Community. Participants Twenty-nine thousand five hundred forty-four women aged 65 and older enrolled in the WHI-OS and free of disability in activities of daily living (ADLs) at baseline. Measurements Geriatric syndromes (high depressive symptoms, dizziness, falls, hearing or visual impairment, osteoporosis, polypharmacy, syncope, sleep disturbance, and urinary incontinence) were self-reported at baseline and 3-year follow-up. Disability was defined as dependence in any ADL and was assessed at baseline and follow-up. Chronic diseases were measured according to a modified Charlson Index. Results Geriatric syndromes were common in this population of women; 76.3% had at least one syndrome at baseline. Greater number of geriatric syndromes at baseline was significantly associated with greater risk of incident ADL disability at follow-up (P.001). Adjusted risk ratios were 1.21 (95% confidence interval (CI)=0.781.87) for a single syndrome and 6.64 (95% CI=4.1510.62) for five or more syndromes compared with no syndromes. These results were only slightly attenuated after adjustment for number of chronic diseases or pain. Conclusion Geriatric syndromes are significantly associated with onset of disability in older women; this association is not simply a result of chronic disease or pain. A better understanding of how these conditions contribute to disablement is needed. Geriatric syndrome assessment should be considered along with chronic disease management in the prevention of disability in older women.
Details
- Title: Subtitle
- Geriatric Syndromes and Incident Disability in Older Women: Results from the Women's Health Initiative Observational Study
- Creators
- Andrea L. Rosso - University of PittsburghCharles B. Eaton - Memorial Hospital of Rhode IslandRobert Wallace - University of IowaRachel Gold - Kaiser Permanente Center for Health ResearchMarcia L. Stefanick - Stanford UniversityJudith K. Ockene - University of Massachusetts Chan Medical SchoolJ. David Curb - University of Hawaiʻi at MānoaYvonne L. Michael - Drexel University
- Resource Type
- Journal article
- Publication Details
- Journal of the American Geriatrics Society (JAGS), Vol.61(3), pp.371-379
- DOI
- 10.1111/jgs.12147
- PMID
- 23452034
- PMCID
- PMC3602348
- NLM abbreviation
- J Am Geriatr Soc
- ISSN
- 0002-8614
- eISSN
- 1532-5415
- Publisher
- Wiley
- Number of pages
- 9
- Grant note
- P30AG024827 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) HHSN268201100046C; HHS N268201100001C; HHSN268201100002C; HHSN26820 1100003C; HHSN268201100004C; HHSN27120110 0004C / National Heart, Lung, and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) R03AG031973 / National Institute of Aging; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA)
- Language
- English
- Date published
- 03/01/2013
- Academic Unit
- Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984364448602771
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