Journal article
Glaucoma-associated corneal endothelial cell damage: A review
Survey of Ophthalmology, Vol.63(4), pp.500-506
07/2018
DOI: 10.1016/j.survophthal.2017.11.002
PMID: 29146208
Abstract
The corneal endothelium is critical in maintaining a healthy and clear cornea. Corneal endothelial cells have a significant reserve function, but preservation of these cells is paramount as they have limited regenerative capacity. Glaucoma is a prevalent disease, and damage to the corneal endothelium may be caused by the disease process itself as well as by its treatment. The mechanisms involved in glaucoma-associated damage to the corneal endothelium need further investigation. Understanding how glaucoma and glaucoma surgery impact the endothelium is important for protecting corneal clarity and visual acuity in all glaucoma patients, including those undergoing corneal transplant. We will discuss a range of identified factors that may impact corneal endothelial cell health in glaucoma, including intraocular pressure, glaucoma medications, surgical glaucoma management, mechanical forces, and alterations in the aqueous environment.
Details
- Title: Subtitle
- Glaucoma-associated corneal endothelial cell damage: A review
- Creators
- Ben J JansonWallace L AlwardYoung H KwonDaniel I BettisJohn H FingertLorraine M ProvencherKenneth M GoinsMichael D WagonerMark A Greiner
- Resource Type
- Journal article
- Publication Details
- Survey of Ophthalmology, Vol.63(4), pp.500-506
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.survophthal.2017.11.002
- PMID
- 29146208
- ISSN
- 0039-6257
- eISSN
- 1879-3304
- Language
- English
- Date published
- 07/2018
- Academic Unit
- Internal Medicine; Ophthalmology and Visual Sciences
- Record Identifier
- 9983979957902771
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