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Global Aphasia Without Hemiparesis
Journal article   Peer reviewed

Global Aphasia Without Hemiparesis

Daniel Tranel, José Biller, Hanna Damasio, Harold P Adams and Steven H Cornell
Archives of neurology (Chicago), Vol.44(3), pp.304-308
03/01/1987
DOI: 10.1001/archneur.1987.00520150050021
PMID: 3827682

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Abstract

Three patients acutely developed global aphasia, but did not manifest the typical accompanying right hemiparesis. Computed tomography and magnetic resonance imaging studies demonstrated that the patients had two discrete left hemisphere lesions, one in the anterior language cortices or language-related subcortical areas, and one in the posterior language cortices. Cerebral angiography showed that two patients had complete occlusion of the left internal carotid artery, and the third had an intraluminal "clot" in the supraclinoid portion of the left internal carotid, findings suggestive of an embolic etiology. Our cases indicate that global aphasia without hemiparesis predicts two discrete lesions and a particularly good recovery of speech and language.

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