Journal article
Global experience and perspective on anonymous nondirected live donation in living donor liver transplantation
Clinical transplantation, Vol.34(4), pp.e13836-n/a
04/2020
DOI: 10.1111/ctr.13836
PMID: 32154620
Abstract
Anonymous nondirected living liver donation (ANLLD), sometimes referred to as “altruistic” donation, occurs when a biologically unrelated person comes forward to donate a portion of his/her liver to a transplant candidate who is unknown to the donor. Here, we explore the current status of ANLLD with special consideration of published reports; US experience; impact on donor psychosocial outcomes; barriers to donation; and current global trends with respect to ethical considerations. Between 1998 and 2019, 105 anonymous nondirected living liver donor (ND‐LLD) transplants have been documented in the US Scientific Registry of Transplant Recipients. Sixteen donors (15%) were reported to experience a postoperative complication. Currently, 89 donors remain alive (85%), 16 (15%) have unknown status, and none are confirmed deceased. Although there are only a handful of case series, these data suggest that ANLLD is a feasible option. While there are no liver‐specific data, studies involving anonymous nondirected kidney donors suggest that anonymous donation does not adversely impact psychosocial outcomes in donors or recipients. There are substantial financial burdens and ethical considerations related to ANLLD. Further studies are required to assess donor demographics, psychosocial motivations, long‐term health‐related quality of life, and financial impact of ANLLD.
Details
- Title: Subtitle
- Global experience and perspective on anonymous nondirected live donation in living donor liver transplantation
- Creators
- Muhammad H. Raza - University of Southern CaliforniaHassan Aziz - University of Southern CaliforniaNavpreet Kaur - University of Southern CaliforniaMary Lo - University of Southern CaliforniaLinda Sher - University of Southern CaliforniaYuri Genyk - University of Southern CaliforniaJuliet Emamaullee - University of Southern California
- Resource Type
- Journal article
- Publication Details
- Clinical transplantation, Vol.34(4), pp.e13836-n/a
- DOI
- 10.1111/ctr.13836
- PMID
- 32154620
- ISSN
- 0902-0063
- eISSN
- 1399-0012
- Number of pages
- 10
- Language
- English
- Date published
- 04/2020
- Academic Unit
- Surgery
- Record Identifier
- 9984701546502771
Metrics
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