Journal article
Global, regional, and national mortality due to unintentional carbon monoxide poisoning, 2000-2021: results from the Global Burden of Disease Study 2021
The Lancet. Public health, Vol.8(11), pp.E839-E849
11/01/2023
DOI: 10.1016/S2468-2667(23)00185-8
PMCID: PMC10602911
PMID: 37813118
Abstract
Background Unintentional carbon monoxide poisoning is a largely preventable cause of death that has received insufficient attention. We aimed to conduct a comprehensive global analysis of the demographic, temporal, and geographical patterns of fatal unintentional carbon monoxide poisoning from 2000 to 2021. Methods As part of the latest Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), unintentional carbon monoxide poisoning mortality was quantified using the GBD cause of death ensemble modelling strategy. Vital registration data and covariates with an epidemiological link to unintentional carbon monoxide poisoning informed the estimates of death counts and mortality rates for all locations, sexes, ages, and years included in the GBD. Years of life lost (YLLs) were estimated by multiplying deaths by remaining standard life expectancy at age of death. Population attributable fractions (PAFs) for unintentional carbon monoxide poisoning deaths due to occupational injuries and high alcohol use were estimated. Findings In 2021, the global mortality rate due to unintentional carbon monoxide poisoning was 0 center dot 366 per 100 000 (95% uncertainty interval 0 center dot 276-0 center dot 415), with 28 900 deaths (21 700-32 800) and 1 center dot 18 million YLLs (0 center dot 886-1 center dot 35) across all ages. Nearly 70% of deaths occurred in males (20 100 [15 800-24 000]), and the 50-54-year age group had the largest number of deaths (2210 [1660-2590]). The highest mortality rate was in those aged 85 years or older with 1 center dot 96 deaths (1 center dot 38-2 center dot 32) per 100 000. Eastern Europe had the highest age-standardised mortality rate at 2 center dot 12 deaths (1 center dot 98-2 center dot 30) per 100 000. Globally, there was a 53 center dot 5% (46 center dot 2-63 center dot 7) decrease in the age-standardised mortality rate from 2000 to 2021, although this decline was not uniform across regions. The overall PAFs for occupational injuries and high alcohol use were 13 center dot 6% (11 center dot 9-16 center dot 0) and 3 center dot 5% (1 center dot 4-6 center dot 2), respectively. Interpretation Improvements in unintentional carbon monoxide poisoning mortality rates have been inconsistent across regions and over time since 2000. Given that unintentional carbon monoxide poisoning is almost entirely preventable, policy-level interventions that lower the risk of carbon monoxide poisoning events should be prioritised, such as those that increase access to improved heating and cooking devices, reduce carbon monoxide emissions from generators, and mandate use of carbon monoxide alarms. Funding Bill & Melinda Gates Foundation. Copyright (c) 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
Details
- Title: Subtitle
- Global, regional, and national mortality due to unintentional carbon monoxide poisoning, 2000-2021: results from the Global Burden of Disease Study 2021
- Creators
- Madeline E. Moberg - University of WashingtonErin B. Hamilton - University of WashingtonScott M. Zeng - University of WashingtonDana Bryazka - University of WashingtonJeff T. Zhao - University of WashingtonRachel Feldman - University of WashingtonYohannes Habtegiorgis Abate - Aleta Wondo Hosp, Dept Clin Governance & Quality Improvement, Aleta Wondo, EthiopiaMohsen Abbasi-Kangevari - University of TehranAme Mehadi Abdurehman - Haramaya UniversityAidin Abedi - Univ Southern Calif, Dept Neurosurg, Los Angeles, CA USAEman Abu-Gharbieh - University of SharjahIsaac Yeboah Addo - UNSW SydneyAbiola Victor Adepoju - HIV & Infect Dis Dept, Abuja, NigeriaQorinah Estiningtyas Sakilah Adnani - Univ Padjadjaran, Dept Fac Med, Bandung, IndonesiaSaira Afzal - King Edward Mem Hosp, Dept Community Med, Lahore, PakistanBright Opoku Ahinkorah - University of Technology SydneySajjad Ahmad - Abasyn UniversityDanial Ahmed - NYIT Coll Osteopath Med, Dept Life Sci, Old Westbury, NY USAHaroon Ahmed - COMSATS Inst Informat Technol, Dept Biosci, Islamabad, PakistanDejene Tsegaye Alem - Debre Markos UniversityAdel Ali Saeed Al-Gheethi - Tun Hussein Onn University of MalaysiaYousef Alimohamadi - Iran Univ Med Sci, Pars Adv & Minimally Invas Med Manners Res Ctr, Tehran, IranEdward Kwabena Ameyaw - Lingnan UniversityMohammad Amrollahi-Sharifabadi - Lorestan UniversityTadele Fentabil Anagaw - Bahir Dar UniversityAnayochukwu Edward Anyasodor - Charles Sturt UniversityJalal Arabloo - Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, IranAleksandr Y. Aravkin - University of WashingtonSeyyed Shamsadin Athari - Zanjan Univ Med Sci, Dept Immunol, Zanjan, IranAlok Atreya - Lumbini Med Coll, Dept Forens Med, Palpa, NepalAmirhossein Azari Jafari - Shahroud Univ Med Sci, Sch Med, Shahroud, IranAshish D. Badiye - Govt Inst Forens Sci, Dept Forens Sci, Nagpur, Maharashtra, IndiaNayereh Baghcheghi - Saveh Univ Med Sci, Dept Nursing, Saveh, IranSara Bagherieh - Isfahan Univ Med Sci, Sch Med, Esfahan, IranHansi Bansal - Govt Inst Forens Sci, Dept Forens Sci, Nagpur, Maharashtra, IndiaAmadou Barrow - University of the GambiaAzadeh Bashiri - Shiraz UniversityNebiyou Simegnew Bayileyegn - Jimma UniversityAlemshet Yirga Berhie - Bahir Dar UniversityAkshaya Srikanth Bhagavathula - Univ Arkansas, Dept Hlth Human Performance & Recreat, Fayetteville, AR USAPankaj Bhardwaj - All India Inst Med Sci, Dept Community Med & Family Med, Jodhpur, Rajasthan, IndiaArchith Boloor - Manipal Acad Higher Educ, Dept Internal Med, Mangalore, IndiaLuis Alberto Camera - Italian Hosp Buenos Aires, Internal Med Dept, Buenos Aires, DF, ArgentinaFelix CarvalhoMarcia Carvalho - Univ Fernando Pessoa, Fac Hlth Sci, Porto, PortugalEeshwar K. Chandrasekar - University of RochesterJung-Chen Chang - Natl Taiwan Univ, Coll Med, Taipei, TaiwanVijay Kumar Chattu - University of TorontoDinh-Toi Chu - VNUInt Sch, Ctr Biomed & Community Hlth, Hanoi, VietnamKaleb Coberly - University of WashingtonNatalia Cruz-Martins - Polytech & Univ Higher Educ Cooperat, Therapeut & Diagnost Technol, Gandra, PortugalOmid Dadras - Western Norway Univ Appl Sci, Sect Global Hlth & Rehabil, Bergen, NorwayXiaochen Dai - University of WashingtonReza Darvishi Cheshmeh Soltani - Arak UniversitySaswati Das - Minist Hlth & Welfare, Dept Biochem, New Delhi, IndiaSubasish Das - Texas State Univ, Ingram Sch Engn, San Marcos, TX USASisay Abebe Debela - Salale UniversityBerecha Hundessa Demessa - Jimma UniversityXinlei Deng - Natl Inst Hlth, Epidemiol Branch, Durham, NC USAAbebaw Alemayehu Desta - University of GondarBelay Desye - Adigrat UniversityMeghnath Dhimal - Nepal Hlth Res Council, Hlth Res Sect, Kathmandu, NepalMahmoud Dibas - Sulaiman Al Rajhi Univ, Res Unit, Qasim, Saudi ArabiaHaneil Larson Dsouza - Manipal Acad Higher Educ, Dept Forens Med & Toxicol, Mangalore, IndiaMichael Ekholuenetale - University of IbadanIman El Sayed - Alexandria UniversityWaseem El-Huneidi - University of SharjahDaniel Berhanie Enyew - Haramaya UniversityAdeniyi Francis Fagbamigbe - University of IbadanAli Fatehizadeh - Isfahan Univ Med Sci, Dept Environm Hlth Engn, Esfahan, IranSyeda Anum Fatima Fatima - University of OsloFlorian Fischer - Charité - Universitätsmedizin BerlinRichard Charles Franklin - James Cook UniversityTushar Garg - King Edward Mem Hosp, Dept Radiol, Mumbai, Maharashtra, IndiaTilaye Gebru Gebi - Haramaya UniversityUrge Gerema - Jimma UniversityMelaku Getachew - Haramaya UniversityMotuma Erena Getachew - Jimma UniversityFarhad Ghamari - Arak UniversityMahaveer Golechha - Indian Inst Publ Hlth, Hlth Syst & Policy Res Dept, Gandhinagar, IndiaPouya Goleij - Sana Inst Higher Educ, Dept Genet, Sari, IranSapna Gupta - Shriram Inst Ind Res, Toxicol Dept, Delhi, IndiaVeer Bala Gupta - Deakin UniversityVivek Kumar Gupta - Macquarie UniversityMehdi Harorani - Arak UniversityHamidreza Hasani - Iran Univ Med Sci, Dept Ophthalmol, Karaj, IranAbbas M. Hassan - Univ Texas Houston, Dept Plast Surg, Houston, TX USAHossein Hassanian-Moghaddam - Shahid Beheshti UniversityMohammed Bheser Hassen - University of WashingtonSimon I. Hay - University of WashingtonKhezar Hayat - Univ Vet & Anim Sci, Inst Pharmaceut Sci, Lahore, PakistanMohammad Heidari - Shahrekord UniversityMahsa Heidari-Foroozan - Shahid Beheshti UniversityDemisu Zenbaba Heyi - Madda Walabu UniversityRamesh Holla - Kasturba Med Coll & Hosp, Mangalore, IndiaPraveen Hoogar - Apollo Univ, Sch Social Sci, Chittoor, IndiaMd Shakhaoat Hossain - Jahangirnagar UniversityMohammad-Salar Hosseini - Tabriz Univ Med Sci, Res Ctr Evidence Based Med, Tabriz, IranSorin Hostiuc - Carol Davila Univ Med & Pharm, Dept Legal Med & Bioeth, Bucharest, RomaniaSoodabeh Hoveidamanesh - Shahid Motahari Hosp, Burn Res Ctr, Tehran, IranGBD 2021 Carbon Monoxide Poisoning CollaboratorsDavid C Schwebel (Contributor) - Research Administration
- Resource Type
- Journal article
- Publication Details
- The Lancet. Public health, Vol.8(11), pp.E839-E849
- DOI
- 10.1016/S2468-2667(23)00185-8
- PMID
- 37813118
- PMCID
- PMC10602911
- NLM abbreviation
- Lancet Public Health
- ISSN
- 2468-2667
- eISSN
- 2468-2667
- Publisher
- Elsevier
- Number of pages
- 11
- Grant note
- Bill AMP; Melinda Gates Foundation; CGIAR
- Language
- English
- Date published
- 11/01/2023
- Academic Unit
- Research Administration
- Record Identifier
- 9984949464802771
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