Journal article
Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice
Thrombosis and haemostasis, Vol.99(2), pp.264-270
2008
DOI: 10.1160/TH07-10-0638
PMID: 18278173
Abstract
Summary
The von Willebrand factor (VWF) receptor complex, glycoprotein (GP)Ib-V-IX, and its main ligand VWF play a key role in the adhesion process of platelets to sites of vascular injury. Recent studies in mutant mice have shed new light on the importance of either molecule for the development of arterial and venous thrombosis. In this review, we summarize the most important aspects from these studies.
Details
- Title: Subtitle
- Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice
- Creators
- Wolfgang BergmeierAnil K ChauhanDenisa D Wagner
- Resource Type
- Journal article
- Publication Details
- Thrombosis and haemostasis, Vol.99(2), pp.264-270
- Publisher
- Schattauer GmbH
- DOI
- 10.1160/TH07-10-0638
- PMID
- 18278173
- ISSN
- 0340-6245
- eISSN
- 2567-689X
- Grant note
- 0630044N / American Heart Association Scientist Development
- Language
- English
- Date published
- 2008
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984094396902771
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