Journal article
Gradient theories of brain activation: A novel application to studying the parental brain
Current behavioral neuroscience reports, Vol.6(3), pp.119-125
09/2019
DOI: 10.1007/s40473-019-00182-5
PMCID: PMC7062306
PMID: 32154064
Abstract
Parental brain research primarily employs general-linear-model-based (GLM-based) analyses to assess blood-oxygenation-level-dependent responses to infant auditory and visual cues, reporting common responses in shared cortical and subcortical structures. However, this approach does not reveal intermixed neural substrates related to different sensory modalities. We consider this notion in studying the parental brain.
Spatial independent component analysis (sICA) has been used to separate mixed source signals from overlapping functional networks. We explore relative differences between GLM-based analysis and sICA as applied to an fMRI dataset acquired from women while they listened to infant cries or viewed infant sad faces.
There is growing appreciation for the value of moving beyond GLM-based analyses to consider brain functional organization as continuous, distributive, and overlapping gradients of neural substrates related to different sensory modalities. Preliminary findings suggest sICA can be applied to the study of the parental brain.
Details
- Title: Subtitle
- Gradient theories of brain activation: A novel application to studying the parental brain
- Creators
- Helena J V Rutherford - Child Study Center, Yale University School of Medicine, New Haven, CT 06510, United StatesJiansong Xu - Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United StatesPatrick D Worhunsky - Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United StatesRubin Zhang - Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United StatesSarah W Yip - Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United StatesKristen P Morie - Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United StatesVince D Calhoun - Dept of Electrical and Computer Engineering, The University of New Mexico, Albuquerque, NM, 87131, United StatesSohye Kim - Center for Reproductive Psychiatry, Pavilion for Women, Texas Children's HospitalLane Strathearn - Stead Family Department of Pediatrics, University of Iowa Carver College of MedicineLinda C Mayes - Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United StatesMarc N Potenza - The Connecticut Mental Health Center, New Haven, CT 06519, United States
- Resource Type
- Journal article
- Publication Details
- Current behavioral neuroscience reports, Vol.6(3), pp.119-125
- DOI
- 10.1007/s40473-019-00182-5
- PMID
- 32154064
- PMCID
- PMC7062306
- NLM abbreviation
- Curr Behav Neurosci Rep
- ISSN
- 2196-2979
- eISSN
- 2196-2979
- Publisher
- Switzerland
- Grant note
- K23 HD043097 / NICHD NIH HHS K01 DA039299 / NIDA NIH HHS R03 HD080998 / NICHD NIH HHS R01 MH118695 / NIMH NIH HHS P20 GM103472 / NIGMS NIH HHS R01 DA006025 / NIDA NIH HHS R01 DA026437 / NIDA NIH HHS K01 DA042937 / NIDA NIH HHS K01 DA042998 / NIDA NIH HHS R01 EB020407 / NIBIB NIH HHS R03 DA045289 / NIDA NIH HHS R01 DA039136 / NIDA NIH HHS R01 HD065819 / NICHD NIH HHS
- Language
- English
- Date published
- 09/2019
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Developmental and Behavioral Pediatrics; Neuroscience and Pharmacology
- Record Identifier
- 9984040214702771
Metrics
28 Record Views