Journal article
Guideline-concordant breast cancer care by patient race and ethnicity accounting for individual-, facility- and area-level characteristics: a SEER-Medicare study
Cancer causes & control, Vol.35(7), pp.1017-1031
03/28/2024
DOI: 10.1007/s10552-024-01859-3
PMCID: PMC11706205
PMID: 38546924
Abstract
Purpose
To examine racial–ethnic variation in adherence to established quality metrics (NCCN guidelines and ASCO quality metrics) for breast cancer, accounting for individual-, facility-, and area-level factors.
Methods
Data from women diagnosed with invasive breast cancer at 66+ years of age from 2000 to 2017 were examined using SEER-Medicare. Associations between race and ethnicity and guideline-concordant diagnostics, locoregional treatment, systemic therapy, documented stage, and oncologist encounters were estimated using multilevel logistic regression models to account for clustering within facilities or counties.
Results
Black and American Indian/Alaska Native (AIAN) women had consistently lower odds of guideline-recommended care than non-Hispanic White (NHW) women (Diagnostic workup: ORBlack 0.83 (0.79–0.88), ORAIAN 0.66 (0.54–0.81); known stage: ORBlack 0.87 (0.80–0.94), ORAIAN 0.63 (0.47–0.85); seeing an oncologist: ORBlack 0.75 (0.71–0.79), ORAIAN 0.60 (0.47–0.72); locoregional treatment: ORBlack 0.80 (0.76–0.84), ORAIAN 0.84 (0.68–1.02); systemic therapies: ORBlack 0.90 (0.83–0.98), ORAIAN 0.66 (0.48–0.91)). Commission on Cancer accreditation and facility volume were significantly associated with higher odds of guideline-concordant diagnostics, stage, oncologist visits, and systemic therapy. Black residential segregation was associated with significantly lower odds of guideline-concordant locoregional treatment and systemic therapy. Rurality and area SES were associated with significantly lower odds of guideline-concordant diagnostics and oncologist visits.
Conclusions
This is the first study to examine guideline-concordance across the continuum of breast cancer care from diagnosis to treatment initiation. Disparities were present from the diagnostic phase and persisted throughout the clinical course. Facility and area characteristics may facilitate or pose barriers to guideline-adherent treatment and warrant future investigation as mediators of racial–ethnic disparities in breast cancer care.
Details
- Title: Subtitle
- Guideline-concordant breast cancer care by patient race and ethnicity accounting for individual-, facility- and area-level characteristics: a SEER-Medicare study
- Creators
- Emma L Herbach - University of MiamiMichaela Curran - University of IowaMya L Roberson - University of North Carolina at Chapel HillRyan M Carnahan - University of IowaBradley D McDowell - University of IowaKai Wang - Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USAIngrid Lizarraga - University of IowaSarah H Nash - University of IowaMary Charlton - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Cancer causes & control, Vol.35(7), pp.1017-1031
- DOI
- 10.1007/s10552-024-01859-3
- PMID
- 38546924
- PMCID
- PMC11706205
- NLM abbreviation
- Cancer Causes Control
- eISSN
- 1573-7225
- Grant note
- P30 CA086862 / NCI NIH HHS
- Language
- English
- Electronic publication date
- 03/28/2024
- Academic Unit
- Epidemiology; Biostatistics; Surgery; Nursing; Center for Social Science Innovation; Injury Prevention Research Center; Community and Behavioral Health; Holden Comprehensive Cancer Center
- Record Identifier
- 9984577034702771
Metrics
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