Journal article
HIV-1 plasma RNA level and CD4 cell count in a large urban HIV-1-infected patient population from 1997 to 2000
International journal of STD & AIDS, Vol.14(11), pp.740-744
2003
DOI: 10.1258/09564620360719778
PMID: 14624736
Abstract
We evaluated the change in plasma HIV-1 RNA level and CD4 cell counts in an HIV-1-infected population between 1997 and 2000. Both the mean and the median values of plasma HIV-1 RNA level decreased with time with the exception of 1998. The mean and medians for CD4 cell count appear to be fairly stable. While the percentage of patients with plasma HIV-1 RNA level <400 copies/mL increased from 29.12% in 1997 to 41.31% in 2000, the percentage of patients with plasma HIV-1 RNA level >100,000 copies/mL remained fairly constant.
The availability of HAART had impacted the level of plasma HIV-1 RNA, although many patients still have plasma HIV-1 RNA level >100,000 copies/mL. Most patients with plasma HIV-1 RNA level >400 copies/mL in 1997 still have plasma HIV-1 RNA level >400 copies/mL in 2000. These laboratory findings, however, do not necessarily mean that there had been a lack of clinical benefit.
Details
- Title: Subtitle
- HIV-1 plasma RNA level and CD4 cell count in a large urban HIV-1-infected patient population from 1997 to 2000
- Creators
- Hua Shan - Department of Pathology, School of Medicine, Johns Hopkins Medical Institutions, Pathology 311 C, 600 North Wolfe Street, Baltimore, MD 21287, United StatesEstelle PIWOWAR-MANNING - Department of Pathology, School of Medicine, Johns Hopkins Medical Institutions, Pathology 311 C, 600 North Wolfe Street, Baltimore, MD 21287, United StatesRichard E THOMPSON - Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United StatesJ. Brooks JACKSON - Department of Pathology, School of Medicine, Johns Hopkins Medical Institutions, Pathology 311 C, 600 North Wolfe Street, Baltimore, MD 21287, United States
- Resource Type
- Journal article
- Publication Details
- International journal of STD & AIDS, Vol.14(11), pp.740-744
- Publisher
- Royal Society of Medicine Press; London
- DOI
- 10.1258/09564620360719778
- PMID
- 14624736
- ISSN
- 0956-4624
- eISSN
- 1758-1052
- Language
- English
- Date published
- 2003
- Academic Unit
- Pathology; VPMA - Administration
- Record Identifier
- 9984046825602771
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