HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, China

Liu Wei; Jie Chen; Michelle Rodolph; Geetha Beauchamp; Ben Mâsse; Rongjian Li; Shaoping Wang; Yuhua Ruan; Shenghan Lai; Li Zhang; Feng Zhou; Scott M Rose; Thomas Perdue; Yiming Shao; J Brooks Jackson

doi:10.1300/j465v27n04_07

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HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, China

Journal article

Peer reviewed

HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, China

Liu Wei, Jie Chen, Michelle Rodolph, Geetha Beauchamp, Ben Mâsse, Rongjian Li, Shaoping Wang, Yuhua Ruan, Shenghan Lai, Li Zhang, …

Substance abuse, Vol.27(4), pp.53-61

12/2006

DOI: 10.1300/j465v27n04_07

PMID: 17347126

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Abstract

A prospective observational study of HIV seroincidence among high-risk injection drug users (IDU) was carried out in Guangxi, China. The primary objectives of this study were (1) to estimate HIV seroincidence (2) to estimate participant retention rate and (3) to evaluate changes in drug use and sexual behavior over a one year period. Five hundred HIV seronegative IDU were enrolled. HIV-1 incidence and retention rates were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Changes in drug use and sexual behavior were analyzed at the baseline, 6-month and 12-month follow- up visits. At 12 months of follow-up, the HIV-1 incidence rate was 3.1 per 100 person years, [95% CI: (1.6%; 5.2%)] and participant retention rate was 87%. Reported changes in high-risk behaviors over 12-months included significant decreases in the frequency of heroin injection, in direct or indirect sharing of injection equipment, and in the number of sexual partners. HIV incidence is high among IDU in Guangxi, China despite a self-reported decrease in some high risk behaviors over the course of the study.

HIV-1

HIV Infections - prevention & control

Patient Dropouts - statistics & numerical data

Rural Population - statistics & numerical data

Prospective Studies

Follow-Up Studies

Humans

Middle Aged

Substance Abuse, Intravenous - epidemiology

Male

Health Knowledge, Attitudes, Practice

Needle Sharing - statistics & numerical data

Adolescent

Unsafe Sex

Adult

Female

HIV Infections - transmission

HIV Seroprevalence

Cohort Studies

Details

Title: Subtitle: HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, China
Creators: Liu Wei - Guangxi Centers for Disease Control and Prevention, Nanning, China
Jie Chen
Michelle Rodolph
Geetha Beauchamp
Ben Mâsse
Rongjian Li
Shaoping Wang
Yuhua Ruan
Shenghan Lai
Li Zhang
Feng Zhou
Scott M Rose
Thomas Perdue
Yiming Shao
J Brooks Jackson
Resource Type: Journal article
Publication Details: Substance abuse, Vol.27(4), pp.53-61
Publisher: United States
DOI: 10.1300/j465v27n04_07
PMID: 17347126
ISSN: 0889-7077
eISSN: 1547-0164
Grant note: U01 AI048011 / NIAID NIH HHS
Language: English
Date published: 12/2006
Academic Unit: Pathology; VPMA - Administration
Record Identifier: 9984046904202771

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