Journal article
HORMONAL REGULATION OF THE MENSTRUAL CYCLE IN WOMEN WITH BREAST CANCER: EFFECT OF ADJUVANT CHEMOTHERAPY
Clinical endocrinology (Oxford), Vol.10(3), pp.287-296
Received 8 May 1978; revised 16 August 1978; accepted 28 August 1978
03/1979
DOI: 10.1111/j.1365-2265.1979.tb02083.x
PMID: 455742
Abstract
The hormonal features of the menstrual cycle determined by measurement of serum LH, FSH, oestradiol, progesterone and prolactin were normal in thirteen breast cancer patients clinically disease free and not taking anti‐tumour therapy. Results of similar studies during seven menstrual cycles in four patients on an adjuvant therapy programme of L‐phenylalanine mustard (L‐PAM) + 5‐flurouracil (5‐FU) also had normal hormonal characteristics after three to fourteen courses of chemotherapy. Amenorrhoea with elevated gonadotrophins occurred after seven courses of chemotherapy in one 48‐year‐old woman. Adjuvant chemotherapy does not appear to result in major alterations in hormone secretion during menstrual cycles of women who continue to menstruate while on therapy. Copyright © 1979, Wiley Blackwell. All rights reserved
Details
- Title: Subtitle
- HORMONAL REGULATION OF THE MENSTRUAL CYCLE IN WOMEN WITH BREAST CANCER: EFFECT OF ADJUVANT CHEMOTHERAPY
- Creators
- BARRY M. Sherman - University of IowaROBERT B. Wallace - University of IowaPETER R. Jochimsen - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Clinical endocrinology (Oxford), Vol.10(3), pp.287-296
- Edition
- Received 8 May 1978; revised 16 August 1978; accepted 28 August 1978
- DOI
- 10.1111/j.1365-2265.1979.tb02083.x
- PMID
- 455742
- NLM abbreviation
- Clin Endocrinol (Oxf)
- ISSN
- 0300-0664
- eISSN
- 1365-2265
- Publisher
- Blackwell Publishing Ltd
- Number of pages
- 10
- Language
- English
- Date published
- 03/1979
- Academic Unit
- Epidemiology; Surgery; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984363623602771
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