Journal article
HPA axis disturbance in obsessive-compulsive disorder
Psychiatry research, Vol.30(3), pp.243-251
1989
DOI: 10.1016/0165-1781(89)90015-2
PMID: 2694203
Abstract
Twenty nondepressed outpatients with
DSM-III obsessive-compulsive disorder entered a 10-week placebo-controlled study of clomipramine and underwent a 1-mg dexamethasone suppression test (DST) at baseline; 11 had a repeat DST at the end of treatment. Nonsuppression was rare. When compared to 82 previously described outpatients with panic disorder studied in a similar fashion, OCD patients had postdexamethasone cortisol values that were substantially lower and more stable over time. Results within the OCD group closely resembled those from a group of never-ill controls.
Details
- Title: Subtitle
- HPA axis disturbance in obsessive-compulsive disorder
- Creators
- William H Coryell - William H. Coryell, M.D., is Professor of Psychiatry, University of Iowa, Iowa City, IA, USADonald W Black - Donald W. Black, M.D., is Assistant Professor of Psychiatry, University of Iowa, Iowa City, IA, USAMichael W Kelly - Russell Noyes, Jr., M.D., is Professor of Psychiatry, Department of Psychiatry, University of Iowa, Iowa City, IA, USARussell Noyes - Michael W. Kelly, Pharm.D., is Clinical Pharmacology Fellow, Department of Pharmacology, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Psychiatry research, Vol.30(3), pp.243-251
- Publisher
- Elsevier Ireland Ltd
- DOI
- 10.1016/0165-1781(89)90015-2
- PMID
- 2694203
- ISSN
- 0165-1781
- eISSN
- 1872-7123
- Language
- English
- Date published
- 1989
- Academic Unit
- Psychiatry; Pharmacy Practice and Science
- Record Identifier
- 9984003929502771
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