Journal article
HPA axis hyperactivity and recovery from functional psychoses
The American journal of psychiatry, Vol.146(4), pp.473-477
04/1989
DOI: 10.1176/ajp.146.4.473
PMID: 2929747
Abstract
Some patients with functional psychoses follow a chronic, deteriorating course and others recover; at present clinicians have essentially no established factors beyond diagnosis and chronicity to predict which course a psychotic patient might follow. Because data on diagnostic specificity suggested that the dexamethasone suppression test might provide another, much needed prognostic factor, the authors administered these tests to 98 consecutively admitted patients with nonmanic psychoses. High postdexamethasone cortisol levels (6 micrograms/dl or higher) at baseline predicted recovery from psychosis at 1 year, independent of episode chronicity and diagnosis. Diagnosis did not correspond well to test results but was itself an important predictor.
Details
- Title: Subtitle
- HPA axis hyperactivity and recovery from functional psychoses
- Creators
- W H Coryell - Department of Psychiatry, University of Iowa, Iowa City 52242M Zimmerman
- Resource Type
- Journal article
- Publication Details
- The American journal of psychiatry, Vol.146(4), pp.473-477
- Publisher
- United States
- DOI
- 10.1176/ajp.146.4.473
- PMID
- 2929747
- ISSN
- 0002-953X
- eISSN
- 1535-7228
- Grant note
- RR-59 / NCRR NIH HHS MH 38777 / NIMH NIH HHS
- Language
- English
- Date published
- 04/1989
- Academic Unit
- Psychiatry
- Record Identifier
- 9984004091902771
Metrics
13 Record Views