Journal article
Haemorrhagic cystitis: a review of management strategies and emerging treatments
BJU international, Vol.132(6), pp.631-637
12/2023
DOI: 10.1111/bju.16140
PMID: 37501638
Abstract
Haemorrhagic cystitis (HC) is characterised by persistent haematuria and lower urinary tract symptoms following radiotherapy or chemotherapy. Its pathogenesis is poorly understood but thought to be related to acrolein toxicity following chemotherapy or fibrosis/vascular remodelling after radiotherapy. There is no standard of care for patients with HC, although existing strategies including fulguration, hyperbaric oxygen therapy, botulinum toxin A, and other intravesical therapies have demonstrated short-term efficacy in cohort studies. Novel agents including liposomal tacrolimus are promising targets for further research. This review summarises the incidence and pathogenesis of HC as well as current evidence supporting its different management strategies.
Details
- Title: Subtitle
- Haemorrhagic cystitis: a review of management strategies and emerging treatments
- Creators
- Kevin D Li - University of California, San FranciscoCharles P Jones - University of California, San FranciscoNizar Hakam - University of California, San FranciscoBradley A EricksonAlex J Vanni - Lahey Medical CenterMichael B Chancellor - Oakland UniversityBenjamin N Breyer - University of California, San Francisco
- Resource Type
- Journal article
- Publication Details
- BJU international, Vol.132(6), pp.631-637
- DOI
- 10.1111/bju.16140
- PMID
- 37501638
- NLM abbreviation
- BJU Int
- eISSN
- 1464-410X
- Language
- English
- Electronic publication date
- 07/28/2023
- Date published
- 12/2023
- Academic Unit
- Urology
- Record Identifier
- 9984453333202771
Metrics
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