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Haptoglobin Genotype as a Determinant of Benefit or Harm from Niacin for Participants with Diabetes
Journal article   Open access   Peer reviewed

Haptoglobin Genotype as a Determinant of Benefit or Harm from Niacin for Participants with Diabetes

Rabea Asleh, Nina S Levy, Gheorge Doros, Tina Costacou, Jennifer G Robinson, Shany Blum, Hagit Goldenstein, William E Boden, Debra L Simmons, Megan A Lacy, …
Journal of the American College of Cardiology, Vol.67(21), pp.2553-2554
2016
DOI: 10.1016/j.jacc.2016.03.533
PMID: 27230052
url
https://doi.org/10.1016/j.jacc.2016.03.533View
Published (Version of record) Open Access

Abstract

One hypothesis that may explain the apparent failure of recent trials of high-density lipoprotein (HDL)-raising therapy is based on the finding that HDL may become proatherogenic under certain circumstances [(1,2)][1], with the proposed result that raising HDL levels in these individuals would be

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