Head and neck muscle spasm after radiotherapy: management with botulinum toxin A injection

Douglas J Van Daele; Eileen M Finnegan; Robert L Rodnitzky; Weining Zhen; Timothy M McCulloch; Henry T Hoffman

doi:10.1001/archotol.128.8.956

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Head and neck muscle spasm after radiotherapy: management with botulinum toxin A injection

Journal article

Peer reviewed

Head and neck muscle spasm after radiotherapy: management with botulinum toxin A injection

Douglas J Van Daele, Eileen M Finnegan, Robert L Rodnitzky, Weining Zhen, Timothy M McCulloch and Henry T Hoffman

Archives of otolaryngology--head & neck surgery, Vol.128(8), pp.956-959

08/2002

DOI: 10.1001/archotol.128.8.956

PMID: 12162778

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Abstract

To introduce the concept of neck muscle pain and spasm after radiotherapy and its treatment with botulinum toxin A. Case series. Ambulatory patients at a tertiary care medical center. Individuals who had undergone primary or adjuvant radiotherapy for treatment of carcinoma of the head and neck were asked about painful spasms of the neck musculature. A volunteer sample was used. If they desired treatment with botulinum toxin A, they were included in the study. Patients received botulinum toxin A injections to the affected sternocleidomastoid muscle(s) in 1 or 2 locations. Subjective pain relief. Four of 6 patients with painful tightness of the neck who received botulinum toxin A injections to the sternocleidomastoid muscle achieved pain relief. A subset of patients with irradiation-induced cervical muscle spasm benefit from treatment with botulinum toxin A injections. Further study is needed to more clearly define the entity and treatment.

Humans

Middle Aged

Male

Neck Muscles - drug effects

Treatment Outcome

Neuromuscular Agents - therapeutic use

Radiotherapy - adverse effects

Injections, Intramuscular

Botulinum Toxins, Type A - administration & dosage

Botulinum Toxins, Type A - therapeutic use

Head and Neck Neoplasms - radiotherapy

Pain - drug therapy

Neck Muscles - radiation effects

Spasm - drug therapy

Neuromuscular Agents - administration & dosage

Pain - etiology

Female

Aged

Spasm - etiology

Pain Measurement

Details

Title: Subtitle: Head and neck muscle spasm after radiotherapy: management with botulinum toxin A injection
Creators: Douglas J Van Daele - Department of Otolaryngology-Head and Neck Surgery, University of Iowa Health Care, Iowa City 52242, USA. douglas-van-daele@uiowa.edu
Eileen M Finnegan
Robert L Rodnitzky
Weining Zhen
Timothy M McCulloch
Henry T Hoffman
Resource Type: Journal article
Publication Details: Archives of otolaryngology--head & neck surgery, Vol.128(8), pp.956-959
DOI: 10.1001/archotol.128.8.956
PMID: 12162778
NLM abbreviation: Arch Otolaryngol Head Neck Surg
ISSN: 0886-4470
eISSN: 1538-361X
Publisher: American Medical Association; United States
Language: English
Date published: 08/2002
Academic Unit: Neurology; Communication Sciences and Disorders; Radiation Oncology; Medicine Administration; Otolaryngology
Record Identifier: 9984006435102771

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