Journal article
Health Perceptions in Patients Who Undergo Screening and Workup for Prostate Cancer
Urology (Ridgewood, N.J.), Vol.69(2), pp.215-220
2007
DOI: 10.1016/j.urology.2006.09.059
PMCID: PMC1868466
PMID: 17320653
Abstract
False-positive screening tests may induce persistent psychological distress. This study was designed to determine whether a positive screening test with negative biopsy findings for prostate cancer is associated with worsened mental health during short-term follow-up.
We conducted a cross-sectional telephone survey of two groups of men approximately 2 months after testing: group 1, 109 men with an abnormal prostate-specific antigen level or digital rectal examination findings but with negative biopsy findings for prostate cancer; and group 2, 101 age-matched primary care patients with PSA screening levels in the reference range (less than 4 ng/mL). Primary outcomes included state anxiety and prostate cancer-related worry. Secondary outcomes included Medical Outcomes Study Short Form 36-item Health Survey subscales and sexual function items. Multivariate regression techniques were used to adjust for differences in baseline covariates.
Group 1 patients were more worried than group 2 patients about getting prostate cancer (mean worry 3.9 versus 4.5,
P = 0.0001, using a 5-point scale, with 1 indicating extreme worry and 5 no worry). Group 1 patients also perceived their risk of prostate cancer to be significantly greater than that of controls (
P = 0.001). No significant differences were found across state anxiety or Medical Outcomes Study Short Form 36-item Health Survey subscales. Sexual bother was greater for group 1 patients, with 19% reporting that sexual function was a moderate to big problem compared with 10% of group 2 patients (
P = 0.0001).
Men with abnormal prostate cancer screening tests report increased cancer-related worry and more problems with sexual function, despite having a negative biopsy result. Effective counseling interventions are needed before prostate cancer screening and during follow-up.
Details
- Title: Subtitle
- Health Perceptions in Patients Who Undergo Screening and Workup for Prostate Cancer
- Creators
- David A Katz - Departments of Medicine and Epidemiology, University of Iowa Carver College of Medicine and College of Public Health, Iowa City, IowaDavid F Jarrard - Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WisconsinColleen A McHorney - Regenstrief Institute, Indiana University School of Medicine and Veterans Affairs Health Services Research and Development, Indianapolis, IndianaStephen L Hillis - Center for Research in Innovative Strategies and Practices, Iowa City Veterans Affairs Medical Center, Iowa City, IowaDonald A Wiebe - Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WisconsinDennis G Fryback - Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
- Resource Type
- Journal article
- Publication Details
- Urology (Ridgewood, N.J.), Vol.69(2), pp.215-220
- DOI
- 10.1016/j.urology.2006.09.059
- PMID
- 17320653
- PMCID
- PMC1868466
- NLM abbreviation
- Urology
- ISSN
- 0090-4295
- eISSN
- 1527-9995
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 2007
- Academic Unit
- Radiology; Epidemiology; Biostatistics; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984094545802771
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