Journal article
Heart Failure in the Era of Precision Medicine: A Scientific Statement From the American Heart Association
Circulation. Genomic and precision medicine, Vol.12(10), pp.458-485
10/01/2019
DOI: 10.1161/HCG.0000000000000058
PMID: 31510778
Abstract
One of 5 people will develop heart failure over his or her lifetime. Early diagnosis and better understanding of the pathophysiology of this disease are critical to optimal treatment. The "omics"-genomics, pharmacogenomics, epigenomics, proteomics, metabolomics, and microbiomics- of heart failure represent rapidly expanding fields of science that have, to date, not been integrated into a single body of work. The goals of this statement are to provide a comprehensive overview of the current state of these omics as they relate to the development and progression of heart failure and to consider the current and potential future applications of these data for precision medicine with respect to prevention, diagnosis, and therapy.
Details
- Title: Subtitle
- Heart Failure in the Era of Precision Medicine: A Scientific Statement From the American Heart Association
- Creators
- Sharon Cresci - CardiologyNaveen L. Pereira - Cardiovascular MedicineFerhaan Ahmad - Univ Iowa, Carver Coll Med, Iowa City, IA 52242 USAMirnela Byku - Univ N Carolina, Chapel Hill, NC 27515 USALisa de las Fuentes - CardiologyDavid E. Lanfear - Henry Ford Hosp, Detroit, MI 48202 USACarolyn M. Reilly - Emory UniversityAnjali T. Owens - Univ Penn, Ctr Inherited Cardiovasc Dis, Perelman Sch Med, Philadelphia, PA 19104 USAMatthew J. Wolf - Univ Virginia, Charlottesville, VA 22903 USAAmerican Heart Association Council on Genomic and Precision MedicineCouncil on Cardiovascular and Stroke NursingCouncil on Quality of Care and Outcomes Research
- Resource Type
- Journal article
- Publication Details
- Circulation. Genomic and precision medicine, Vol.12(10), pp.458-485
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1161/HCG.0000000000000058
- PMID
- 31510778
- ISSN
- 2574-8300
- eISSN
- 2574-8300
- Number of pages
- 28
- Grant note
- R01 HL103871 / NHLBI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI)
- Language
- English
- Date published
- 10/01/2019
- Academic Unit
- Radiology; Molecular Physiology and Biophysics; Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
- Record Identifier
- 9984297509202771
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