Helicobacter pylori infection in patients with epilepsy

Ali A. Asadi-Pooya; Seyed Mohsen Dehghani; Peyman Petramfar; Mehrdad Emami; Mojtaba Mahmoodi

doi:10.1016/j.seizure.2011.08.011

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Helicobacter pylori infection in patients with epilepsy

Journal article

Open access

Peer reviewed

Helicobacter pylori infection in patients with epilepsy

Ali A. Asadi-Pooya, Seyed Mohsen Dehghani, Peyman Petramfar, Mehrdad Emami and Mojtaba Mahmoodi

Seizure (London, England), Vol.21(1), pp.21-23

01/01/2012

DOI: 10.1016/j.seizure.2011.08.011

PMID: 21903421

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Abstract

Background: The possible role of Helicobacter pylori (HP) infection in extra-intestinal diseases has been suggested. The main purpose of this study was to determine the frequency of infection with HP in two groups of patients with epilepsy: patients with idiopathic generalized epilepsy (ICE) and patients with temporal lobe epilepsy (TLE), compared to healthy controls. Methods: In this cross-sectional study a random sample of adult patients above 18 years of age with a diagnosis of ICE or TLE were recruited at the outpatient epilepsy clinic at Shiraz University of Medical Sciences, from January 2009 through June 2011. A group of healthy individuals were included as control group. For all patients and controls a urea breath test (UBT) was requested. Results: Thirty-four patients with ICE, 28 patients with TLE and 33 individuals as control were recruited. Positive UBT was observed in 21 individuals (61.8%) with ICE, 50% (14 patients) of patients with TLE and 72.7% (24 individuals) in control group. The difference between patients with IGE and control group was not significant (P = 0.3). The difference between patients with TLE and control group was not significant either (P = 0.068). Conclusion: The rate of HP infection was not higher in patients with epilepsy compared to healthy individuals. At the moment, there is not enough epidemiological data to support the role of HP infection in patients with either ICE or TLE. (C) 2011 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Clinical Neurology

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

Details

Title: Subtitle: Helicobacter pylori infection in patients with epilepsy
Creators: Ali A. Asadi-Pooya - Shiraz University of Medical Sciences
Seyed Mohsen Dehghani - Shiraz University of Medical Sciences
Peyman Petramfar - Shiraz University of Medical Sciences
Mehrdad Emami - Shiraz University of Medical Sciences
Mojtaba Mahmoodi - Shiraz University of Medical Sciences
Resource Type: Journal article
Publication Details: Seizure (London, England), Vol.21(1), pp.21-23
DOI: 10.1016/j.seizure.2011.08.011
PMID: 21903421
NLM abbreviation: Seizure
ISSN: 1059-1311
eISSN: 1532-2688
Publisher: Elsevier
Number of pages: 3
Grant note: Shiraz University of Medical Sciences; Shiraz University of Medical Science
Language: English
Date published: 01/01/2012
Academic Unit: Neurology
Record Identifier: 9985013726802771

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