Hematolymphoid Neoplasm Mimicking Endodontic Lesions: Case series and Review of the Literature

Wattawan Wongpattaraworakul; Tadkamol Krongbaramee; Emily A. Lanzel; John W. Hellstein; Fabricio B. Teixeira

doi:10.1016/j.oooo.2024.07.011

Back

Hematolymphoid Neoplasm Mimicking Endodontic Lesions: Case series and Review of the Literature

Journal article

Peer reviewed

Hematolymphoid Neoplasm Mimicking Endodontic Lesions: Case series and Review of the Literature

Wattawan Wongpattaraworakul, Tadkamol Krongbaramee, Emily A. Lanzel, John W. Hellstein and Fabricio B. Teixeira

Oral surgery, oral medicine, oral pathology and oral radiology, Vol.139(1), pp.e1-e12

01/2025

DOI: 10.1016/j.oooo.2024.07.011

PMID: 39179451

View Online

Abstract

Hematolymphoid neoplasms originating in the periapical region of a tooth are rare occurrences. Their signs, symptoms, and radiographic findings can also mimic lesions of endodontic origin. History-taking and clinical examination provide clues to determine the possibility of a non-endodontic lesion, although the definitive diagnosis can only be rendered based on histologic examination. In our case series, we present four cases of hematolymphoid neoplasms that radiographically mimicked endodontic lesions. All the cases initially underwent endodontic treatment, but the lesions failed to resolve. In one case, the clinician suspected a diagnosis of lymphoma based on the patient's history. In the other cases, the clinicians' impression was that the lesions originated from endodontic issues. We present two cases of diffuse large B-cell lymphoma, a case of a plasma cell neoplasm, and a case of Langerhans cell histiocytosis, along with a literature review of three entities when found in the oral cavity as well as review of hematolymphoid neoplasm mimicking endodontic lesion previously reported in literature.

Biopsy

diffuse large B-cell lymphoma

endodontic lesions

hematolymphoid neoplasm

histopathology

Langerhans cell histiocytosis

non-endodontic lesions

periapical lesions

plasma cell neoplasm

Details

Title: Subtitle: Hematolymphoid Neoplasm Mimicking Endodontic Lesions: Case series and Review of the Literature
Creators: Wattawan Wongpattaraworakul - University of Iowa
Tadkamol Krongbaramee - Chiang Mai University
Emily A. Lanzel - University of Iowa
John W. Hellstein - University of Iowa
Fabricio B. Teixeira - Department of Endodontics, College of Dentistry and Dental Clinics, University of Iowa, Iowa City, Iowa
Resource Type: Journal article
Publication Details: Oral surgery, oral medicine, oral pathology and oral radiology, Vol.139(1), pp.e1-e12
DOI: 10.1016/j.oooo.2024.07.011
PMID: 39179451
NLM abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol
ISSN: 2212-4403
eISSN: 2212-4411
Publisher: Elsevier Inc
Language: English
Electronic publication date: 08/2024
Date published: 01/2025
Academic Unit: Oral Pathology, Radiology and Medicine; Endodontics
Record Identifier: 9984696702602771

Metrics

12 Record Views

1 Times Cited - Web of Science