Hemispheric differences for P300 amplitude from an auditory oddball task

Joel E Alexander; Lance O Bauer; Samuel Kuperman; Sandra Morzorati; Sean J O'Connor; John Rohrbaugh; Bernice Porjesz; Henri Begleiter; John Polich

doi:10.1016/0167-8760(95)00047-X

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Hemispheric differences for P300 amplitude from an auditory oddball task

Journal article

Peer reviewed

Hemispheric differences for P300 amplitude from an auditory oddball task

Joel E Alexander, Lance O Bauer, Samuel Kuperman, Sandra Morzorati, Sean J O'Connor, John Rohrbaugh, Bernice Porjesz, Henri Begleiter and John Polich

International journal of psychophysiology, Vol.21(2), pp.189-196

1996

DOI: 10.1016/0167-8760(95)00047-X

PMID: 8792206

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Abstract

The P3(00) event-related potential (ERP) was elicited in 80 normal, right-handed male subjects using a simple auditory stimulus discrimination task, with electroencephalographic (EEG) activity recorded at 19 electrodes. P300 amplitude was larger over the right compared to left hemisphere electrode sites primarily at anterior-medial locations (F3/4, C3/4) for both target and standard stimuli. The N100, P200, and N200 components also demonstrated several similar, albeit less robust, hemispheric asymmetries. No hemispheric effects for P300 latency were observed, with few consistent latency findings for any of the other components obtained. The results suggest that the discrimination process underlying P300 generation may originate with right frontal activation.

P300

Event-related potential (ERP)

Hemispheric differences

Auditory stimulus

Details

Title: Subtitle: Hemispheric differences for P300 amplitude from an auditory oddball task
Creators: Joel E Alexander - Department of Psychology, Western Oregon State College, Monmouth, OR 97361, USA
Lance O Bauer - Department of Psychiatry, University of Connecticut Health Center., Farmington, CT 06030, USA
Samuel Kuperman - Department of Psychiatry, University of Iowa, Iowa City, IA 52242, USA
Sandra Morzorati - Department of Psychiatry, Institute of Psychiatric Research, Indianapolis, IN 46202, USA
Sean J O'Connor - Department of Psychiatry, Institute of Psychiatric Research, Indianapolis, IN 46202, USA
John Rohrbaugh - Department of Psychiatry, Washington University, St. Louis, MO 63108, USA
Bernice Porjesz - Department of Psychiatry, SUNY Health Sciences Center, Brooklyn, NY 11203, USA
Henri Begleiter - Department of Psychiatry, SUNY Health Sciences Center, Brooklyn, NY 11203, USA
John Polich - Department ofNeuropharmacology, TPC-10, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, USA
Resource Type: Journal article
Publication Details: International journal of psychophysiology, Vol.21(2), pp.189-196
Publisher: Elsevier B.V
DOI: 10.1016/0167-8760(95)00047-X
PMID: 8792206
ISSN: 0167-8760
eISSN: 1872-7697
Language: English
Date published: 1996
Academic Unit: Psychiatry; Stead Family Department of Pediatrics
Record Identifier: 9984004083402771

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