Journal article
Hemodynamic precision to guide surgical timing for neonates with congenital diaphragmatic hernia: a narrative review
Journal of perinatology, Vol.45(4), pp.552-561
04/2025
DOI: 10.1038/s41372-025-02265-6
PMID: 40108476
Abstract
Despite a near universal approach focused on physiologic stabilization prior to surgical repair of congenital diaphragmatic hernia (CDH), a condition with significant morbidity and mortality, there remains a lack of consensus, or even guidance, on the appropriate timing for diaphragmatic reconstruction. Hemodynamic-directed care has increasingly been incorporated into the post-natal, peri-operative care of CDH, including assessments of pulmonary hypertension and ventricular dysfunction. Herein, we discuss the integration of targeted neonatal echocardiography and hemodynamic-based assessments to guide precision-directed care and inform selection of the optimal surgical repair window in this complex, heterogeneous patient population.
Details
- Title: Subtitle
- Hemodynamic precision to guide surgical timing for neonates with congenital diaphragmatic hernia: a narrative review
- Creators
- John T Wren Jr - University of Iowa, NeonatologyNeil Patel - Royal Hospital for ChildrenMatthew T Harting - Memorial HermannPatrick J McNamara - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.45(4), pp.552-561
- DOI
- 10.1038/s41372-025-02265-6
- PMID
- 40108476
- NLM abbreviation
- J Perinatol
- ISSN
- 1476-5543
- eISSN
- 1476-5543
- Publisher
- SPRINGERNATURE
- Language
- English
- Electronic publication date
- 03/19/2025
- Date published
- 04/2025
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984801841902771
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