Journal article
Hemodynamics in infants with hypoxemic ischemic encephalopathy: pathophysiology and beyond
Journal of perinatology
12/01/2025
DOI: 10.1038/s41372-025-02516-6
PMID: 41326752
Abstract
Perinatal asphyxia is a critical event causing variable degrees of multiorgan dysfunction. Hypoxemic ischemic encephalopathy (HIE) features the brain exposure to asphyxia, and most of the underlying pathophysiology is a related to impaired blood flow and oxygen delivery to the brain. Cardiovascular compromise is common in this context and often necessitates initiation of inotropic support. In this article, we highlight the neonatal hemodynamics and its derangements, following asphyxia, and we highlight the pitfalls in the current hemodynamic approach.
Details
- Title: Subtitle
- Hemodynamics in infants with hypoxemic ischemic encephalopathy: pathophysiology and beyond
- Creators
- Aimann Surak - University of AlbertaGeorg M Schmölzer - University of AlbertaPatrick J McNamara - University of IowaJoseph Y Ting - University of AlbertaMusab Alshareef - Alberta Children's Hospital Research InstituteKhorshid Mohammad - Alberta Children's Hospital Research Institute
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology
- DOI
- 10.1038/s41372-025-02516-6
- PMID
- 41326752
- NLM abbreviation
- J Perinatol
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Publisher
- Springer Nature
- Language
- English
- Electronic publication date
- 12/01/2025
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9985090729802771
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