Journal article
Hemorrhage after coronary artery bypass graft procedures
Infection control and hospital epidemiology, Vol.24(1), pp.44-50
01/2003
DOI: 10.1086/502114
PMID: 12558235
Abstract
To identify risk factors for excessive bleeding after coronary artery bypass graft (CABG) procedures and to quantify the outcomes related to this complication.
We conducted a case-control study to identify risk factors for hemorrhage following CABG surgery and a historical cohort study to quantify outcomes of hemorrhage.
The cardiothoracic surgery service of a university hospital.
Factors associated with excessive blood loss were recent catheterization (odds ratio [OR] = 0.44; 95% confidence interval [CI95], 0.21 to 0.91); age older than 65 years (OR = 1.94; CI95, 0.96 to 3.93); bypass time of 150 minutes or more (OR = 2.91; CI95, 1.09 to 7.81); and postoperative platelet count of 160,000/mm3 or less (OR = 2.36; CI95, 1.06 to 5.22). The attributable cost of a postoperative hemorrhage was $3,866 (P = .0002) overall, $9,912 (P = .0001) for patients who required reoperation, and $3,316 (P = .03) for those treated medically. The median attributable postoperative length of stay was 1 day longer for cases than for controls (P = .011). Postoperatively, patients who hemorrhaged received significantly larger volumes of packed red blood cells (P < .0001), fresh frozen plasma (P < .0001), platelets (P < .0001), plasminate (P = .007), protamine sulfate (P < .0001), desmopressin acetate (P < .0001), and epsilon-aminocaproic acid (P < .0001) than did controls.
Age, duration of bypass, and postoperative platelet count were associated with excessive bleeding. Hemorrhage after CABG surgery significantly increased the length of stay and cost of care.
Details
- Title: Subtitle
- Hemorrhage after coronary artery bypass graft procedures
- Creators
- Loreen A Herwaldt - Department of Internal Medicine, University of Iowa College of Medicine, USASheri K SwartzendruberM Bridget ZimmermanDavid A ScholzJo Ann FranklinChristopher A Caldarone
- Resource Type
- Journal article
- Publication Details
- Infection control and hospital epidemiology, Vol.24(1), pp.44-50
- Publisher
- United States
- DOI
- 10.1086/502114
- PMID
- 12558235
- ISSN
- 0899-823X
- eISSN
- 1559-6834
- Language
- English
- Date published
- 01/2003
- Academic Unit
- Infectious Diseases; Epidemiology; Biostatistics; Internal Medicine
- Record Identifier
- 9983997481402771
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