Journal article
Hepatocellular carcinoma: From diagnosis to treatment
World journal of hepatology, Vol.7(8), pp.1020-1029
05/18/2015
DOI: 10.4254/wjh.v7.i8.1020
PMCID: PMC4450179
PMID: 26052391
Abstract
Hepatocellular carcinoma (HCC) is the sixth most prevalent malignancy worldwide and is a rising cause of cancer related mortality. Risk factors for HCC are well documented and effective surveillance and early diagnosis allow for curative therapies. The majority of HCC appears to be caused by cirrhosis from chronic hepatitis B and hepatitis C virus. Preventive strategies include vaccination programs and anti-viral treatments. Surveillance with ultrasonography detects early stage disease and improves survival rates. Many treatment options exist for individuals with HCC and are determined by stage of presentation. Liver transplantation is offered to patients who are within the Milan criteria and are not candidates for hepatic resection. In patients with advanced stage disease, sorafenib shows some survival benefit.
Details
- Title: Subtitle
- Hepatocellular carcinoma: From diagnosis to treatment
- Creators
- Abhijeet Waghray - Abhijeet Waghray, Department of Medicine, MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH 44109, United StatesArvind R Murali - Abhijeet Waghray, Department of Medicine, MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH 44109, United StatesKv Narayanan Menon - Abhijeet Waghray, Department of Medicine, MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH 44109, United States
- Resource Type
- Journal article
- Publication Details
- World journal of hepatology, Vol.7(8), pp.1020-1029
- DOI
- 10.4254/wjh.v7.i8.1020
- PMID
- 26052391
- PMCID
- PMC4450179
- NLM abbreviation
- World J Hepatol
- ISSN
- 1948-5182
- eISSN
- 1948-5182
- Language
- English
- Date published
- 05/18/2015
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094361202771
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