Journal article
Heterogeneity in 12-month outcome among female and male smokers
Addiction (Abingdon, England), Vol.99(2), pp.237-250
02/2004
DOI: 10.1111/j.1360-0443.2003.00629.x
PMID: 14756716
Abstract
To examine heterogeneity in outcome following treatment for smoking cessation with combined bupropion SR and behavioral counseling in women and men.
This study included 875 women and 649 men recruited from a large health-care system and randomized to one of four combinations of treatment [two dosage levels of bupropion SR (Zyban, 150 mg and 300 mg) were crossed with two counseling programs of lower and higher intensity to create a four-cell design].
A comprehensive set of relevant individual characteristics prior to treatment and treatment characteristics was included in the analysis. Smoking outcome at 12 months was defined as point-prevalence of any regular smoking within the 7 days prior to follow-up contact. Classification and regression tree analysis identified six subgroups in women that ranged in proportion of non-smokers from 9.8% to 42.9% and six subgroups in men that ranged in proportion of non-smokers from 17.3% to 50.0%.
These results indicate the presence of a substantial amount of variation in treatment outcome among women and men receiving combined bupropion SR and counseling. Variation in outcome could be reduced by providing treatments tailored to subgroups of individuals who are at exceptionally high risk for smoking following cessation.
Details
- Title: Subtitle
- Heterogeneity in 12-month outcome among female and male smokers
- Creators
- Gary E Swan - Group Health CooperativeHarold S Javitz - Group Health CooperativeLisa M Jack - Group Health CooperativeSusan J Curry - Group Health CooperativeTim McAfee - Group Health Cooperative
- Resource Type
- Journal article
- Publication Details
- Addiction (Abingdon, England), Vol.99(2), pp.237-250
- DOI
- 10.1111/j.1360-0443.2003.00629.x
- PMID
- 14756716
- ISSN
- 0965-2140
- eISSN
- 1360-0443
- Grant note
- R01 CA071358 / NCI NIH HHS CA71358 / NCI NIH HHS
- Language
- English
- Date published
- 02/2004
- Academic Unit
- Health Management and Policy; Community and Behavioral Health
- Record Identifier
- 9984366375102771
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