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Hiding in Plain Sight: A Novel Microbial Driver for Colorectal Cancer?
Editorial   Open access

Hiding in Plain Sight: A Novel Microbial Driver for Colorectal Cancer?

Tejeshwar Jain and Vikas Dudeja
Cancer discovery, Vol.12(8), pp.1838-1840
08/05/2022
DOI: 10.1158/2159-8290.CD-22-0612
PMID: 35929130
url
https://doi.org/10.1158/2159-8290.CD-22-0612View
Published (Version of record) Open Access

Abstract

In this issue of Cancer Discovery, Drewes and colleagues demonstrate a surprising role for the common gut pathogen Clostridioides difficile in driving colorectal cancer in preclinical models through the bacterial toxin-dependent reprogramming of the epithelial and immune compartments. See related article by Drewes et al., p. 1873 (3).
Oncology Life Sciences & Biomedicine Science & Technology

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