High-resolution CT vascular imaging using blood pool contrast agents

Ananth V Annapragada; Eric Hoffman; Abhay Divekar; Efstathios Karathanasis; Ketan B Ghaghada

doi:10.14797/mdcj-8-1-18

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High-resolution CT vascular imaging using blood pool contrast agents

Journal article

Open access

Peer reviewed

High-resolution CT vascular imaging using blood pool contrast agents

Ananth V Annapragada, Eric Hoffman, Abhay Divekar, Efstathios Karathanasis and Ketan B Ghaghada

Methodist DeBakey cardiovascular journal, Vol.8(1), pp.18-22

01/2012

DOI: 10.14797/mdcj-8-1-18

PMCID: PMC3405778

PMID: 22891106

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https://europepmc.org/articles/pmc3405778View

Published (Version of record) Open Access

Abstract

While the evolution of computed tomography imaging in the last 2 decades has been driven almost exclusively by improvements in the instrumentation and processing algorithms, there have been comparatively modest advances in contrast agent technology.A notable change in the last decade has been the development of blood pool contrast agents based on nanoparticle technology.While not yet ready for clinical use, the stable and uniform opacification provided by these agents in normal vasculature and controlled extravasation in compromised vasculature enables novel techniques for imaging and diagnosis of pathologies. This manuscript presents preclinical examples demonstrating cardiovascular pathologies and tumor characterization by high-resolution computed tomography imaging.

Animals

Cardiology - methods

Cardiovascular Diseases - diagnostic imaging

Contrast Media

Humans

Nanomedicine

Nanoparticles

Predictive Value of Tests

Tomography, X-Ray Computed

Whole Body Imaging

Details

Title: Subtitle: High-resolution CT vascular imaging using blood pool contrast agents
Creators: Ananth V Annapragada - Texas Children's Hospital
Eric Hoffman - Roy J. and Lucille A. Carver College of Medicine
Abhay Divekar - Roy J. and Lucille A. Carver College of Medicine
Efstathios Karathanasis - Case Western Reserve University
Ketan B Ghaghada - Texas Children's Hospital
Resource Type: Journal article
Publication Details: Methodist DeBakey cardiovascular journal, Vol.8(1), pp.18-22
DOI: 10.14797/mdcj-8-1-18
PMID: 22891106
PMCID: PMC3405778
NLM abbreviation: Methodist Debakey Cardiovasc J
ISSN: 1947-6108
eISSN: 1947-6108
Grant note: 2R44EB04700 / NIBIB NIH HHS P30 CA043703 / NCI NIH HHS
Language: English
Date published: 01/2012
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Stead Family Department of Pediatrics; Internal Medicine
Record Identifier: 9984318702902771

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