Journal article
Higher salt preference in heart failure patients
Appetite, Vol.58(1), pp.418-423
2012
DOI: 10.1016/j.appet.2011.09.021
PMID: 22019543
Abstract
► Heart failure (HF) patients present intense activation of neural and humoral factors. ► HF patients may exhibit an enhanced avidity for salty tastes. ► Intensity of salt preference in HF patients and normal healthy volunteers was tested. ► Stable HF patients present a higher preference for salt than healthy volunteers.
Heart failure (HF) is a complex syndrome that involves changes in behavioral, neural and endocrine regulatory systems. Dietary salt restriction along with pharmacotherapy is considered an essential component in the effective management of symptomatic HF patients. However, it is well recognized that HF patients typically have great difficulty in restricting sodium intake. We hypothesized that under HF altered activity in systems that normally function to regulate body fluid and cardiovascular homeostasis could produce an increased preference for the taste of salt. Therefore, this study was conducted to evaluate the perceived palatability (defined as salt preference) of food with different concentrations of added salt in compensated chronically medicated HF patients and comparable control subjects. Healthy volunteers (
n
=
25) and medicated, clinically stable HF patients (
n
=
38, NYHA functional class II or III) were interviewed and given an evaluation to assess their preferences for different amounts of saltiness. Three salt concentrations (0.58, 0.82, and 1.16
g/100
g) of bean soup were presented to the subjects. Salt preference for each concentration was quantified using an adjective scale (unpleasant, fair or delicious). Healthy volunteers preferred the soup with medium salt concentration (
p
=
0.042), HF patients disliked the low concentration (
p
<
0.001) and preferred the high concentration of salted bean soup (
p
<
0.001). When compared to healthy volunteers, HF patients demonstrated a significantly greater preference for the soup with a high salt concentration (
p
=
0.038). It is concluded that medicated, compensated patients under chronic treatment for HF have an increased preference for salt.
Details
- Title: Subtitle
- Higher salt preference in heart failure patients
- Creators
- Juli Thomaz de Souza - Department of Physiology, Institute of Bioscience, UNESP-Botucatu, BrazilLuiz S Matsubara - Department of Internal Medicine, Botucatu Medical School, BrazilJosé Vanderlei Menani - Department of Physiology and Pathology, FOAr, UNESP-Araraquara, São Paulo State University, UNESP, São Paulo, BrazilBeatriz B Matsubara - Department of Internal Medicine, Botucatu Medical School, BrazilAlan Kim Johnson - Department of Psychology, University of Iowa, Iowa City, IA 52242-1407, USAJuliana Irani Fratucci De Gobbi - Department of Physiology, Institute of Bioscience, UNESP-Botucatu, Brazil
- Resource Type
- Journal article
- Publication Details
- Appetite, Vol.58(1), pp.418-423
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.appet.2011.09.021
- PMID
- 22019543
- ISSN
- 0195-6663
- eISSN
- 1095-8304
- Language
- English
- Date published
- 2012
- Academic Unit
- Psychological and Brain Sciences; Neuroscience and Pharmacology; Health and Human Physiology
- Record Identifier
- 9984002330202771
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