Journal article
Histologic Evaluation of the Testicular Remnant Associated with the Vanishing Testes Syndrome: Is Surgical Management Necessary?
Urology (Ridgewood, N.J.), Vol.70(6), pp.1204-1206
2007
DOI: 10.1016/j.urology.2007.08.020
PMID: 18158048
Abstract
There is controversy surrounding the optimal management of the testicular remnant associated with the vanishing testes syndrome. Some urologists advocate the need for surgical exploration, whereas others believe this is unnecessary. These differing opinions are based on the variable reports of viable germ cell elements found within the testicular remnants. To better understand the pathology associated with this syndrome and the need for surgical management, we reviewed our experience regarding the incidence of viable germ cell elements within the testicular remnant.
An institutional review board-approved, retrospective review was performed of all consecutive patients undergoing exploration for a nonpalpable testis at Eastern Virginia Medical School and Geisinger Medical Center between 1994 and 2006. Patients who were found to have spermatic vessels and a vas deferens exiting a closed internal inguinal ring were included in this analysis.
Fifty-six patients underwent removal of the testicular remnant. Patient age ranged from 11 to 216 months. In 8 of the specimens (14%), we identified viable germ cell elements. In an additional 4 patients (7%), we identified seminiferous tubules without germ cell elements.
In our review, we identified that a significant number of testicular remnants associated with the vanishing testes syndrome can harbor viable germ cell elements or seminiferous tubules. The exact fate of these residual elements remains unknown; however, there may exist the potential for malignant transformation. Given the potential for malignant degeneration, we believe that these remnants should be removed.
Details
- Title: Subtitle
- Histologic Evaluation of the Testicular Remnant Associated with the Vanishing Testes Syndrome: Is Surgical Management Necessary?
- Creators
- Douglas Storm - Geisinger Medical CenterTimothy Redden - Eastern Virginia Medical SchoolMaria Aguiar - Eastern Virginia Medical SchoolMyra Wilkerson - Geisinger Medical CenterGerald Jordan - Eastern Virginia Medical SchoolJoel Sumfest - Geisinger Medical Center
- Resource Type
- Journal article
- Publication Details
- Urology (Ridgewood, N.J.), Vol.70(6), pp.1204-1206
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.urology.2007.08.020
- PMID
- 18158048
- ISSN
- 0090-4295
- eISSN
- 1527-9995
- Language
- English
- Date published
- 2007
- Academic Unit
- Stead Family Department of Pediatrics; Urology
- Record Identifier
- 9984320857002771
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