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Home noninvasive ventilation use in patients hospitalized with COPD
Journal article   Open access   Peer reviewed

Home noninvasive ventilation use in patients hospitalized with COPD

Spyridon Fortis, Yubo Gao, Kelby Rewerts, Mary Vaughan Sarrazin and Peter J Kaboli
The clinical respiratory journal, Vol.17(8), pp.811-815
08/2023
DOI: 10.1111/crj.13678
PMCID: PMC10435933
PMID: 37525442
url
https://doi.org/10.1111/crj.13678View
Published (Version of record) Open Access

Abstract

Introduction The study objective was to estimate the prevalence of chronic hypercapnic respiratory failure (CHRF) and home noninvasive ventilation (NIV) use in a high-risk population, individuals with a history of at least one COPD-related hospitalizations. Methods We retrospectively analyzed electronic medical record data of patients with at least one COPD-related hospitalization between October 1, 2011, and September 30, 2017, to the Iowa City VA Medical Center. We excluded individuals with no obstructive ventilatory defect. Results Of 186 patients, the overall prevalence of compensated hypercapnic respiratory failure (CompHRF), defined as PaCO2 > 45 mmHg with a pH = 7.35–7.45, was 52.7%, while the overall prevalence of home NIV was 4.3%. The prevalence of CompHRF was 43.6% and home NIV was 1.8% in those with one COPD-related hospitalization. Among those with ≥4 COPD-related hospitalizations, the prevalence of CompHRF was 77.8% (14 of 18), and home NIV was 11.1% (2 of 18). Conclusion Approximately half of individuals with at least one COPD-related hospitalization have CompHRF, but only 8.2% of those use home NIV. Future studies should estimate CHRF rates and the degree of underutilization of home NIV in larger multicenter samples.
UIOWA OA Agreement COPD hypercapnia noninvasive ventilation

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